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James W West

Explore the profile of James W West including associated specialties, affiliations and a list of published articles. Areas
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Citations 464
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Recent Articles
1.
Assi H, Wong C, Tipton K, Mei L, Wong K, Razo J, et al.
Cancer Immunol Res . 2021 Oct; 9(12):1451-1464. PMID: 34635485
Immune-checkpoint blockade has revolutionized cancer treatment. However, most patients do not respond to single-agent therapy. Combining checkpoint inhibitors with other immune-stimulating agents increases both efficacy and toxicity due to systemic...
2.
Desnoyers L, Vasiljeva O, Richardson J, Yang A, Menendez E, Liang T, et al.
Sci Transl Med . 2013 Oct; 5(207):207ra144. PMID: 24132639
Target-mediated toxicity constitutes a major limitation for the development of therapeutic antibodies. To redirect the activity of antibodies recognizing widely distributed targets to the site of disease, we have applied...
3.
Levin S, Taft D, Brandt C, Bucher C, Howard E, Chadwick E, et al.
Eur J Immunol . 2011 Mar; 41(4):902-15. PMID: 21416464
Members of the CD28 family play important roles in regulating T-cell functions and share a common gene structure profile. We have identified VSTM3 as a protein whose gene structure matches...
4.
Kuestner R, Taft D, Haran A, Brandt C, Brender T, Lum K, et al.
J Immunol . 2007 Oct; 179(8):5462-73. PMID: 17911633
The proinflammatory cytokines IL-17A and IL-17F have a high degree of sequence similarity and share many biological properties. Both have been implicated as factors contributing to the progression of inflammatory...