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James Tarver

Explore the profile of James Tarver including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 87
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Recent Articles
1.
Weatherald J, Nathan S, El-Kersh K, Argula R, DuBrock H, Rischard F, et al.
BMJ Open Respir Res . 2024 Mar; 11(1). PMID: 38519114
Background: Inhaled treprostinil (iTre) is the only treatment approved for pulmonary hypertension due to interstitial lung disease (PH-ILD) to improve exercise capacity. This post hoc analysis evaluated clinical worsening and...
2.
Dolan J, Mandras S, Mehta J, Navas V, Tarver J, Chakinala M, et al.
Pulm Circ . 2020 Dec; 10(4):2045894020968471. PMID: 33343880
Pulmonary hypertension currently has minimal guidelines for outpatient disease management. Congestive heart failure studies, however, have shown effectiveness of disease management plans in reducing all-cause mortality and all-cause and congestive...
3.
Bagdanoff J, Donoviel M, Nouraldeen A, Carlsen M, Jessop T, Tarver J, et al.
J Med Chem . 2010 Nov; 53(24):8650-62. PMID: 21090716
Sphingosine 1-phosphate lyase (S1PL) has been characterized as a novel target for the treatment of autoimmune disorders using genetic and pharmacological methods. Medicinal chemistry efforts targeting S1PL by direct in...
4.
Bagdanoff J, Donoviel M, Nouraldeen A, Tarver J, Fu Q, Carlsen M, et al.
J Med Chem . 2009 Jun; 52(13):3941-53. PMID: 19489538
During nearly a decade of research dedicated to the study of sphingosine signaling pathways, we identified sphingosine-1-phosphate lyase (S1PL) as a drug target for the treatment of autoimmune disorders. S1PL...