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James T Brash

Explore the profile of James T Brash including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 168
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Recent Articles
1.
Brash J, Diez-Pinel G, Rinaldi L, Castellan R, Fantin A, Ruhrberg C
Angiogenesis . 2025 Mar; 28(2):21. PMID: 40080216
The vascular endothelial growth factor VEGF drives excessive vascular permeability to cause tissue-damaging oedema in neovascular and inflammatory diseases across multiple organs. Several molecular pathways have been implicated in VEGF-induced...
2.
Dernie F, Corby G, Robinson A, Bezer J, Mercade-Besora N, Griffier R, et al.
Pharmacoepidemiol Drug Saf . 2024 Nov; 33(11):e70042. PMID: 39532529
Purpose: The generation of representative disease phenotypes is important for ensuring the reliability of the findings of observational studies. The aim of this manuscript is to outline a reproducible framework...
3.
Du M, Dernie F, Catala M, Delmestri A, Man W, Brash J, et al.
Eur J Intern Med . 2024 Aug; 130:106-117. PMID: 39134452
Objective: Multiple treatment options are recommended for Systemic Lupus Erythematosus (SLE) by clinical guidelines. This study aimed to explore SLE treatment patterns as there is limited real-world data of SLE...
4.
Brash J, Diez-Pinel G, Colletto C, Castellan R, Fantin A, Ruhrberg C
Nat Cardiovasc Res . 2024 May; 3:460-473. PMID: 38708406
Transcriptomic data can be mined to understand the molecular activity of cell types. Yet, functional genes may remain undetected in RNA sequencing (RNA-seq) experiments for technical reasons, such as insufficient...
5.
Kutikova L, Brash J, Helme K, Brewster J, Brand M, Adam A, et al.
Vaccines (Basel) . 2024 Apr; 12(4). PMID: 38675769
Real-world evidence supports SARS-CoV-2 vaccination strategies during the COVID-19 pandemic. This real-world retrospective study utilized the German Disease Analyzer database to characterize recipients of NVX-CoV2373 and explore vaccination outcomes. Recipients...
6.
Rajwa P, Borkowetz A, Abbott T, Alberti A, Bjartell A, Brash J, et al.
Eur Urol Open Sci . 2024 Apr; 63:81-88. PMID: 38572301
Combination therapies in metastatic hormone-sensitive prostate cancer (mHSPC), which include the addition of an androgen receptor signaling inhibitor and/or docetaxel to androgen deprivation therapy, have been a game changer in...
7.
Lo Re Iii V, Cocoros N, Hubbard R, Dutcher S, Newcomb C, Connolly J, et al.
Clin Epidemiol . 2024 Feb; 16:71-89. PMID: 38357585
Purpose: Few studies have examined how the absolute risk of thromboembolism with COVID-19 has evolved over time across different countries. Researchers from the European Medicines Agency, Health Canada, and the...
8.
Rashbrook V, Brash J, Ruhrberg C
Nat Cardiovasc Res . 2023 Sep; 1:806-816. PMID: 37692772
The Cre-LoxP system provides a widely used method for studying gene requirements in the mouse as the main mammalian genetic model organism. To define the molecular and cellular mechanisms that...
9.
Xie J, Brash J, Turkmen C, Driessen S, Varrassi G, Argyriou G, et al.
Drugs . 2023 Jan; 83(3):249-263. PMID: 36692805
Objective: We aimed to investigate whether ibuprofen use, compared with other non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs), cyclooxygenase-2 inhibitors (COX-2i) or paracetamol, increases the risk of coronavirus disease 2019 (COVID-19) diagnosis...
10.
Brash J, Ruhrberg C, Fantin A
Methods Mol Biol . 2022 Apr; 2475:289-295. PMID: 35451766
Before the endothelial mitogenic activity of the Vascular Endothelial Growth Factor A (VEGF) was described, VEGF had already been identified for its ability to induce vascular leakage. VEGF-induced vascular leakage...