James S O McCullagh
Overview
Explore the profile of James S O McCullagh including associated specialties, affiliations and a list of published articles.
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Articles
64
Citations
825
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Recent Articles
1.
Yalaz C, Bridges E, Alham N, Zois C, Chen J, Bensaad K, et al.
Cancer Metab
. 2025 Jan;
13(1):4.
PMID: 39875986
No abstract available.
2.
Clarke R, Bharucha T, Arman B, Gangadharan B, Fernandez L, Mosca S, et al.
NPJ Vaccines
. 2024 Aug;
9(1):155.
PMID: 39198486
The global population is increasingly reliant on vaccines to maintain population health with billions of doses used annually in immunisation programmes. Substandard and falsified vaccines are becoming more prevalent, caused...
3.
McCullagh J, Keun H
Curr Opin Chem Biol
. 2024 Jul;
81:102498.
PMID: 38981158
No abstract available.
4.
Then C, Paillas S, Moomin A, Misheva M, Moir R, Hay S, et al.
Microbiome
. 2024 May;
12(1):89.
PMID: 38745230
Background: Non-toxic approaches to enhance radiotherapy outcomes are beneficial, particularly in ageing populations. Based on preclinical findings showing that high-fibre diets sensitised bladder tumours to irradiation by modifying the gut...
5.
Noreen H, Smith E, Farman M, Claridge T, McCullagh J
Anal Sci Adv
. 2024 May;
2(7-8):364-372.
PMID: 38715961
Methylated flavones, commonly found in many plants of the Brassicaceae family, have potent antioxidant and anticancer activity with diverse therapeutic potential. However, the specific regioisomers of methylated flavones can have...
6.
Park K, Crump N, Louwman N, Krywawych S, Cheong Y, Vendrell I, et al.
Nat Cardiovasc Res
. 2024 Mar;
2:1221-1245.
PMID: 38500966
Propiogenic substrates and gut bacteria produce propionate, a post-translational protein modifier. In this study, we used a mouse model of propionic acidaemia (PA) to study how disturbances to propionate metabolism...
7.
Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism
John T, Saffoon N, Walsby-Tickle J, Hester S, Dingler F, Millington C, et al.
Chem Sci
. 2024 Feb;
15(7):2509-2517.
PMID: 38362406
Patients with alcoholism and type 2 diabetes manifest altered metabolism, including elevated aldehyde levels and unusually low asparagine levels. We show that asparagine synthetase B (ASNS), the only human asparagine-forming...
8.
Yalaz C, Bridges E, Alham N, Zois C, Chen J, Bensaad K, et al.
Cancer Metab
. 2024 Feb;
12(1):5.
PMID: 38350962
Background: PDE6H encodes PDE6γ', the inhibitory subunit of the cGMP-specific phosphodiesterase 6 in cone photoreceptors. Inhibition of PDE6, which has been widely studied for its role in light transduction, increases...
9.
Emms V, Lewis L, Beja L, Bulman N, Pires E, Muskett F, et al.
Chem Sci
. 2023 Nov;
14(44):12498-12505.
PMID: 38020377
Formaldehyde is a pollutant and human metabolite that is toxic at high concentrations. Biological studies on formaldehyde are hindered by its high reactivity and volatility, which make it challenging to...
10.
Morales-Herrera S, Jourquin J, Coppe F, Lopez-Galvis L, De Smet T, Safi A, et al.
Proc Natl Acad Sci U S A
. 2023 Sep;
120(40):e2302996120.
PMID: 37748053
Plant roots explore the soil for water and nutrients, thereby determining plant fitness and agricultural yield, as well as determining ground substructure, water levels, and global carbon sequestration. The colonization...