James S Leeder
Overview
Explore the profile of James S Leeder including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
49
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0
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Recent Articles
1.
Goldman J, Koen Y, Rogers S, Li K, Leeder J, Hanzlik R
Drug Metab Dispos
. 2016 Jul;
44(10):1603-7.
PMID: 27457783
The formation of drug-protein adducts via metabolic activation and covalent binding may stimulate an immune response or may result in direct cell toxicity. Protein covalent binding is a potentially pivotal...
2.
Kho A, Sharma S, Qiu W, Gaedigk R, Klanderman B, Niu S, et al.
BMC Med Genomics
. 2013 Nov;
6:47.
PMID: 24188128
Background: Poor maternal vitamin D intake is a risk factor for subsequent childhood asthma, suggesting that in utero changes related to vitamin D responsive genes might play a crucial role...
3.
Becker M, van Haandel L, Gaedigk R, Thomas B, Hoeltzel M, Lasky A, et al.
Pharmacogenet Genomics
. 2012 Feb;
22(4):236-46.
PMID: 22344247
Objective: Methotrexate (MTX) has several enzymatic targets in the folate pathway. To better understand the variability in response to MTX, we characterized the interindividual variability of intracellular folate pools in...