» Authors » James R Davie

James R Davie

Explore the profile of James R Davie including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 124
Citations 4236
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Tempel M, Green K, Prajapati D, Duaqui A, Norouzi M, Sattarifard H, et al.
Biochem Cell Biol . 2025 Feb; 103:1-12. PMID: 39951687
Doxorubicin is a chemotherapeutic drug for cancer that intercalates into nucleosome-free regions at promoters. Doxorubicin was reported to result in loss of histone H3 trimethylated lysine 4 (H3K4me3). To further...
2.
Davie J, Sattarifard H, Sudhakar S, Roberts C, Beacon T, Muker I, et al.
Subcell Biochem . 2025 Jan; 108():1-49. PMID: 39820859
The human genome consists of 23 chromosome pairs (22 autosomes and one pair of sex chromosomes), with 46 chromosomes in a normal cell. In the interphase nucleus, the 2 m...
3.
Tahir M, Norouzi M, Khan S, Davie J, Yamanaka S, Ashraf A
Comput Biol Med . 2024 Nov; 183:109302. PMID: 39500240
Epigenetics encompasses mechanisms that can alter the expression of genes without changing the underlying genetic sequence. The epigenetic regulation of gene expression is initiated and sustained by several mechanisms such...
4.
Shahib A, Rastegar M, van Wijnen A, Davie J
Biochem Cell Biol . 2024 Sep; 102(6):430-447. PMID: 39293094
The human lysine acetyltransferases KAT3A () and KAT3B () are essential enzymes in gene regulation in the nucleus. Their ubiquitous expression in metazoan cell types controls cell proliferation and differentiation...
5.
Hendrickson-Rebizant T, Sudhakar S, Rowley M, Frankel A, Davie J, Lakowski T
J Med Chem . 2024 Sep; 67(18):15931-15946. PMID: 39250434
Protein arginine -methyltransferases (PRMT) are a family of -adenosyl-l-methionine (SAM)-dependent enzymes that transfer methyl-groups to the ω-N of arginyl residues in proteins. PRMTs are involved in regulating gene expression, RNA...
6.
Roberts C, Arezoumand K, Kadar Shahib A, Davie J, Rastegar M
Front Cell Dev Biol . 2024 Aug; 12:1413248. PMID: 39108836
Rare neurological diseases include a vast group of heterogenous syndromes with primary impairment(s) in the peripheral and/or central nervous systems. Such rare disorders may have overlapping phenotypes, despite their distinct...
7.
Dashti P, Lewallen E, Gordon J, Montecino M, Davie J, Stein G, et al.
Bone . 2024 Feb; 181:117043. PMID: 38341164
Bone formation and homeostasis are controlled by environmental factors and endocrine regulatory cues that initiate intracellular signaling pathways capable of modulating gene expression in the nucleus. Bone-related gene expression is...
8.
Sudhakar S, Wu L, Patel S, Zovoilis A, Davie J
Biochem Cell Biol . 2023 Nov; 102(2):145-158. PMID: 38011682
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a) is an active histone mark catalyzed by protein arginine methyltransferase 1 (PRMT1), a major arginine methyltransferase in vertebrates catalyzing asymmetric dimethylation of...
9.
Rastegar M, Davie J
Epigenomics . 2023 Nov; 15(20):1027-1031. PMID: 37937403
Tweetable abstract MeCP2 is an epigenetic factor with global impact in epigenome integrity, membrane-less nuclear architecture, and chromatin stability. Our Editorial covers recent advances on these important topics.
10.
Sudhakar S, Khan S, Clark A, Hendrickson-Rebizant T, Patel S, Lakowski T, et al.
Biochem Cell Biol . 2023 Nov; 102(2):106-126. PMID: 37922507
Protein arginine methyltransferase 1 (PRMT1) is a major type I arginine methyltransferase that catalyzes the formation of monomethyl and asymmetric dimethylarginine in protein substrates. It was first identified to asymmetrically...