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James R Beckett

Explore the profile of James R Beckett including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Chhabra M, Shanthamurthy C, Kumar N, Mardhekar S, Vishweshwara S, Wimmer N, et al.
J Med Chem . 2024 Jul; 67(14):11885-11916. PMID: 38995734
Herein, we report the synthesis and biological evaluation of a novel series of heparinoid amphiphiles as inhibitors of heparanase and SARS-CoV-2. By employing a tailor-made synthetic strategy, a library of...
2.
Churchman L, Beckett J, Tan L, Woods K, Doherty D, Ghith A, et al.
J Steroid Biochem Mol Biol . 2024 Feb; 239:106479. PMID: 38346478
Oxidised derivatives of cholesterol have been shown to inhibit the growth of Mycobacterium tuberculosis (Mtb). The bacteriostatic activity of these compounds has been attributed to their inhibition of CYP125A1 and...