James P Landers
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Explore the profile of James P Landers including associated specialties, affiliations and a list of published articles.
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149
Citations
1260
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Recent Articles
1.
Nouwairi R, Jones C, Charette M, Holmquist E, Golabek Z, Landers J
Anal Chem
. 2024 Dec;
97(1):300-311.
PMID: 39731577
Optimizing multireagent assays often requires successive titration of individual components until the optimal combination of conditions is achieved. This process is time-consuming, laborious, and often expensive since parallelized experimentation requires...
2.
OConnell K, Almeida M, Nouwairi R, Costen E, Lawless N, Charette M, et al.
Lab Chip
. 2024 Aug;
24(18):4403-4421.
PMID: 39162068
Presumptive drug screening enables timely procurement of search and arrest warrants and represents a crucial first step in crime scene analysis. Screening also reduces the burden on forensic laboratories which...
3.
Layne T, Scott A, Cunha L, Turiello R, Landers J
Micromachines (Basel)
. 2024 Feb;
15(2).
PMID: 38398999
Isothermal amplification methods have become popular in research due to the simplicity of the technology needed to run the reactions. Specifically, loop-mediated isothermal amplification (LAMP) has been widely used for...
4.
OConnell K, Landers J
Lab Chip
. 2023 Jun;
23(14):3130-3159.
PMID: 37357712
Centrifugal microfluidics has evolved into a sophisticated technology capable of enabling the exploration of fundamental questions in such fields as protein analysis, environmental monitoring, and live cell handling. These microdevices...
5.
Woolf M, Dignan L, Karas S, Lewis H, Kim S, Geise G, et al.
Anal Methods
. 2023 Mar;
15(15):1870-1880.
PMID: 36975002
We report clear proof-of-principle for centrifugally-driven, multiplexed, paper-based orthogonal flow sandwich-style immunocapture (cOFI) and colorimetric detection of Zaire Ebola virus-like particles. Capture antibodies are immobilized onto nanoporous nitrocellulose membranes that...
6.
Woolf M, Cunha L, Hadley K, Moffett R, Landers J
Anal Chim Acta
. 2023 Mar;
1249:340826.
PMID: 36868762
Biological evidence originating from victims of sexual assault is often comprised of unbalanced cellular mixtures with significantly higher contributions from the victim's genetic material. Enrichment of the forensically-critical sperm fraction...
7.
Turiello R, Nouwairi R, Landers J
Forensic Sci Int Genet
. 2023 Jan;
63:102824.
PMID: 36592574
Forensic laboratories are universally acknowledged as being overburdened, underfunded, and in need of improved analytical methods to expedite investigations, decrease the costs associated with nucleic acid (NA) analysis, and perform...
8.
Layne T, Nouwairi R, Fleming R, Blair H, Landers J
Micromachines (Basel)
. 2022 Oct;
13(10).
PMID: 36296010
Initial screening of criminal evidence often involves serological testing of stains of unknown composition and/or origin discovered at a crime scene to determine the tissue of origin. This testing is...
9.
Nouwairi R, Cunha L, Turiello R, Scott O, Hickey J, Thomson S, et al.
Lab Chip
. 2022 Aug;
22(18):3424-3435.
PMID: 35959772
The polymerase chain reaction (PCR) is paramount in nucleic acid amplification testing, and for many assays, the use of PCR or qPCR is considered the 'gold standard'. While instrumentation for...
10.
Dignan L, Karas S, Mighell I, Treene W, Landers J, Woolf M
Anal Chim Acta
. 2022 Aug;
1221:340063.
PMID: 35934337
Rotationally-driven lab-on-a-disc (LoaD) microfluidic systems are among the most promising methods for realizing complex nucleic acid (NA) testing at the point-of-need (PoN). However, despite significant advancements in NA amplification methods,...