James O McInerney
Overview
Explore the profile of James O McInerney including associated specialties, affiliations and a list of published articles.
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84
Citations
2461
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Recent Articles
1.
Richards T, Eme L, Archibald J, Leonard G, Coelho S, de Mendoza A, et al.
PLoS Biol
. 2024 Nov;
22(11):e3002917.
PMID: 39585925
Understanding the origin of eukaryotic cells is one of the most difficult problems in all of biology. A key challenge relevant to the question of eukaryogenesis is reconstructing the gene...
2.
Beavan A, Domingo-Sananes M, McInerney J
Proc Natl Acad Sci U S A
. 2023 Dec;
121(1):e2304934120.
PMID: 38147560
Pangenomes exhibit remarkable variability in many prokaryotic species, much of which is maintained through the processes of horizontal gene transfer and gene loss. Repeated acquisitions of near-identical homologs can easily...
3.
Cummins E, Hall R, Connor C, McInerney J, McNally A
Microb Genom
. 2023 Feb;
8(11).
PMID: 36748558
No abstract available.
4.
McInerney J
Mol Biol Evol
. 2022 Oct;
40(1).
PMID: 36288801
Understanding adaptation to the local environment is a central tenet and a major focus of evolutionary biology. But this is only part of the adaptionist story. In addition to the...
5.
Beavan A, McInerney J
Nat Microbiol
. 2022 Sep;
7(10):1510-1511.
PMID: 36097169
No abstract available.
6.
Cummins E, Hall R, McInerney J, McNally A
Curr Opin Microbiol
. 2022 Feb;
66:73-78.
PMID: 35104691
Prokaryote pangenomes are influenced heavily by environmental factors and the opportunity for gene gain and loss events. As the field of pangenome analysis has expanded, so has the need to...
7.
Hall R, Whelan F, Cummins E, Connor C, McNally A, McInerney J
Microb Genom
. 2021 Sep;
7(9).
PMID: 34499026
The pangenome contains all genes encoded by a species, with the core genome present in all strains and the accessory genome in only a subset. Coincident gene relationships are expected...
8.
Whelan F, Hall R, McInerney J
Mol Biol Evol
. 2021 May;
38(9):3697-3708.
PMID: 33963386
A pangenome is the complete set of genes (core and accessory) present in a phylogenetic clade. We hypothesize that a pangenome's accessory gene content is structured and maintained by selection....
9.
Domingo-Sananes M, McInerney J
Trends Microbiol
. 2021 Jan;
29(6):493-503.
PMID: 33423895
Analyses of multiple whole-genome sequences from the same species have revealed that differences in gene content can be substantial, particularly in prokaryotes. Such variation has led to the recognition of...
10.
Hall R, Whelan F, McInerney J, Ou Y, Domingo-Sananes M
Front Microbiol
. 2020 Aug;
11:1569.
PMID: 32849327
Horizontal gene transfer (HGT) is one of the most important processes in prokaryote evolution. The sharing of DNA can spread neutral or beneficial genes, as well as genetic parasites across...