Alan McNally
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Explore the profile of Alan McNally including associated specialties, affiliations and a list of published articles.
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Articles
122
Citations
2971
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Recent Articles
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Hall R, Snaith A, Element S, Moran R, Smith H, Cummins E, et al.
NPJ Antimicrob Resist
. 2025 Jan;
2(1):11.
PMID: 39843932
Antimicrobial resistance can arise in the natural environment via prolonged exposure to the effluent released by manufacturing facilities. In addition to antibiotics, pharmaceutical plants also produce non-antibiotic pharmaceuticals, both the...
3.
Rizvi S, Chowdhury K, Borsetto C, Travis E, Saif M, Ahmed V, et al.
MethodsX
. 2025 Jan;
14():103122.
PMID: 39830879
Microbial pathogens have developed resistance mechanisms to almost every antibiotic available. There is a need to synthesize or screen new natural compounds to combat the development of drug-resistant pathogens. One...
4.
Snaith A, Moran R, Hall R, Casey A, Ratcliffe L, van Schaik W, et al.
Microb Genom
. 2024 Nov;
10(11).
PMID: 39494554
Vulnerable patients in an intensive care unit (ICU) setting are at high risk of infection from bacteria including gut-colonising and species. Complex ICU procedures often depend on successful antimicrobial treatment,...
5.
Liu H, Moran R, Doughty E, Hua X, Snaith A, Zhang L, et al.
Nat Commun
. 2024 Nov;
15(1):9483.
PMID: 39488505
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a persistent nosocomial pathogen that poses a significant threat to global public health, particularly in intensive care units (ICUs). Here we report a three-month longitudinal...
6.
Ho C, Wong C, Aung T, Lakshminarayanan R, Mehta J, Rauz S, et al.
Lancet Microbe
. 2024 Sep;
6(1):100947.
PMID: 39305919
Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately 5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a multifaceted and cohesive approach...
7.
Quarton S, Livesey A, Jeff C, Hatton C, Scott A, Parekh D, et al.
JMIR Res Protoc
. 2024 Sep;
13:e57334.
PMID: 39293053
Background: Causative pathogens are currently identified in only a minority of pneumonia cases, which affects antimicrobial stewardship. Metagenomic next-generation sequencing (mNGS) has potential to enhance pathogen detection due to its...
8.
Moran R, Behruznia M, Holden E, Garvey M, McNally A
Microb Genom
. 2024 Sep;
10(9).
PMID: 39222339
While conducting genomic surveillance of carbapenemase-producing (CPE) from patient colonisation and clinical infections at Birmingham's Queen Elizabeth Hospital (QE), we identified an N-type plasmid lineage, pQEB1, carrying several antibiotic resistance...
9.
Feng Y, Yang Y, Hu Y, Xiao Y, Xie Y, Wei L, et al.
Cell Rep
. 2024 Aug;
43(8):114602.
PMID: 39137112
Klebsiella aerogenes is an understudied and clinically important pathogen. We therefore investigate its population structure by genome analysis aligned with metadata. We sequence 130 non-duplicated K. aerogenes clinical isolates and...
10.
Quarton S, McGee K, Cumley N, Behruznia M, Jeff C, Belchamber K, et al.
PLoS One
. 2024 Mar;
19(3):e0298425.
PMID: 38551904
Introduction: Infection causes a vast burden of disease, with significant mortality, morbidity and costs to health-care systems. However, identifying the pathogen causative infection can be challenging, resulting in high use...