James N Bussell
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Explore the profile of James N Bussell including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
653
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Recent Articles
1.
Steel L, Tir S, Tam S, Bussell J, Spitschan M, Foster R, et al.
Front Neurosci
. 2022 Jan;
15:832535.
PMID: 35082600
Light is known to exert powerful effects on behavior and physiology, including upon the amount and distribution of activity across the day/night cycle. Here we use home cage activity monitoring...
2.
Tuck E, Estabel J, Oellrich A, Maguire A, Adissu H, Souter L, et al.
Dis Model Mech
. 2015 Sep;
8(11):1467-78.
PMID: 26398943
Knowledge of the expression profile of a gene is a critical piece of information required to build an understanding of the normal and essential functions of that gene and any...
3.
de Angelis M, Nicholson G, Selloum M, White J, Morgan H, Ramirez-Solis R, et al.
Nat Genet
. 2015 Jul;
47(9):969-978.
PMID: 26214591
The function of the majority of genes in the mouse and human genomes remains unknown. The mouse embryonic stem cell knockout resource provides a basis for the characterization of relationships...
4.
Ryder E, Gleeson D, Sethi D, Vyas S, Miklejewska E, Dalvi P, et al.
Mamm Genome
. 2013 Aug;
24(7-8):286-94.
PMID: 23912999
The Sanger Mouse Genetics Project generates knockout mice strains using the EUCOMM/KOMP-CSD embryonic stem (ES) cell collection and characterizes the consequences of the mutations using a high-throughput primary phenotyping screen....
5.
White J, Gerdin A, Karp N, Ryder E, Buljan M, Bussell J, et al.
Cell
. 2013 Jul;
154(2):452-64.
PMID: 23870131
Mutations in whole organisms are powerful ways of interrogating gene function in a realistic context. We describe a program, the Sanger Institute Mouse Genetics Project, that provides a step toward...
6.
Ryder E, Wong K, Gleeson D, Keane T, Sethi D, Vyas S, et al.
Genesis
. 2013 Apr;
51(7):523-8.
PMID: 23620107
We report an albino C57BL/6N mouse strain carrying a spontaneous mutation in the tyrosinase gene (C57BL/6N-Tyr(cWTSI)). Deep whole genome sequencing of founder mice revealed very little divergence from C57BL/6NJ and...
7.
Bartlett N, Walton R, Edwards M, Aniscenko J, Caramori G, Zhu J, et al.
Nat Med
. 2008 Feb;
14(2):199-204.
PMID: 18246079
Rhinoviruses cause serious morbidity and mortality as the major etiological agents of asthma exacerbations and the common cold. A major obstacle to understanding disease pathogenesis and to the development of...