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James N Armitage

Explore the profile of James N Armitage including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 844
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Recent Articles
1.
Horvat-Menih I, McLean M, Zamora-Morales M, Wylot M, Kaggie J, Khan A, et al.
BMJ Open . 2024 Oct; 14(10):e083980. PMID: 39461869
Introduction: Localised renal masses are an increasing burden on healthcare due to the rising number of cases. However, conventional imaging cannot reliably distinguish between benign and malignant renal masses, and...
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Horvat-Menih I, Li H, Priest A, Li S, Gill A, Mendichovszky I, et al.
Eur Radiol Exp . 2024 Jul; 8(1):76. PMID: 38981998
Background: Clinical imaging tools to probe aggressiveness of renal masses are lacking, and T2-weighted imaging as an integral part of magnetic resonance imaging protocol only provides qualitative information. We developed...
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Li R, Ferdinand J, Loudon K, Bowyer G, Laidlaw S, Muyas F, et al.
Cancer Cell . 2022 Nov; 40(12):1583-1599.e10. PMID: 36423636
Tumor behavior is intricately dependent on the oncogenic properties of cancer cells and their multi-cellular interactions. To understand these dependencies within the wider microenvironment, we studied over 270,000 single-cell transcriptomes...
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Ursprung S, Woitek R, McLean M, Priest A, Crispin-Ortuzar M, Brodie C, et al.
Cancers (Basel) . 2022 Jan; 14(2). PMID: 35053497
Differentiating aggressive clear cell renal cell carcinoma (ccRCC) from indolent lesions is challenging using conventional imaging. This work prospectively compared the metabolic imaging phenotype of renal tumors using carbon-13 MRI...
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Welsh S, Thompson N, Warren A, Priest A, Barrett T, Ursprung S, et al.
BJU Int . 2021 Sep; 130(2):244-253. PMID: 34549873
Objective: To explore translational biological and imaging biomarkers for sunitinib treatment before and after debulking nephrectomy in the NeoSun (European Union Drug Regulating Authorities Clinical Trials Database [EudraCT] number: 2005-004502-82)...
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Smith C, Moser T, Mouliere F, Field-Rayner J, Eldridge M, Riediger A, et al.
Genome Med . 2020 Mar; 12(1):23. PMID: 32111235
Background: Cell-free tumor-derived DNA (ctDNA) allows non-invasive monitoring of cancers, but its utility in renal cell cancer (RCC) has not been established. Methods: Here, a combination of untargeted and targeted...
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Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al.
Science . 2019 Oct; 365(6460):1461-1466. PMID: 31604275
Tissue-resident immune cells are important for organ homeostasis and defense. The epithelium may contribute to these functions directly or by cross-talk with immune cells. We used single-cell RNA sequencing to...
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Klatte T, Gallagher K, Afferi L, Volpe A, Kroeger N, Ribback S, et al.
BMC Med . 2019 Oct; 17(1):182. PMID: 31578141
Background: The current World Health Organization classification recognises 12 major subtypes of renal cell carcinoma (RCC). Although these subtypes differ on molecular and clinical levels, they are generally managed as...
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Hsu R, Barclay M, Loughran M, Lyratzopoulos G, Gnanapragasam V, Armitage J
BJU Int . 2019 Jun; 125(1):56-63. PMID: 31206987
Objective: To evaluate the relationship between hospital volume and intermediate- and long-term patient survival for patients undergoing nephrectomy for renal cell carcinoma (RCC). Patients And Methods: Adult patients with RCC...