James M Rosser
Overview
Explore the profile of James M Rosser including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
191
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0
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Recent Articles
1.
Johnson A, Wei J, Rosser J, Kunkele A, Chang C, Reid A, et al.
Cancer Immunol Res
. 2021 Jul;
9(9):1047-1060.
PMID: 34244298
Synthetic immunology, as exemplified by chimeric antigen receptor (CAR) T-cell immunotherapy, has transformed the treatment of relapsed/refractory B cell-lineage malignancies. However, there are substantial barriers-including limited tumor homing, lack of...
2.
Grandi F, Rosser J, Newkirk S, Yin J, Jiang X, Xing Z, et al.
Genome Res
. 2020 Feb;
30(2):313.
PMID: 32079650
No abstract available.
3.
Newkirk S, Lee S, Grandi F, Gaysinskaya V, Rosser J, Vanden Berg N, et al.
Proc Natl Acad Sci U S A
. 2017 Jun;
114(28):E5635-E5644.
PMID: 28630288
The PIWI-interacting RNA (piRNA) pathway is essential for retrotransposon silencing. In piRNA-deficient mice, L1-overexpressing male germ cells exhibit excessive DNA damage and meiotic defects. It remains unknown whether L1 expression...
4.
Grandi F, Rosser J, Newkirk S, Yin J, Jiang X, Xing Z, et al.
Genome Res
. 2015 May;
25(8):1135-46.
PMID: 25995269
Long interspersed elements (LINEs), through both self-mobilization and trans-mobilization of short interspersed elements and processed pseudogenes, have made an indelible impact on the structure and function of the human genome....
5.
Grandi F, Rosser J, An W
Mol Biol Evol
. 2012 Nov;
30(3):503-12.
PMID: 23125228
Interspersed and tandem repeat sequences comprise the bulk of mammalian genomes. Interspersed repeats result from successive replication by transposable elements, such as Alu and long interspersed element type 1 (L1)....
6.
Rosser J, An W
Front Biosci (Elite Ed)
. 2011 Dec;
4(6):2203-25.
PMID: 22202032
Long interspersed elements type 1 (LINE-1s, or L1s) have impacted mammalian genomes at multiple levels. L1 transcription is mainly controlled by its 5' untranslated region (5'UTR), which differs significantly among...
7.
Xie Y, Rosser J, Thompson T, Boeke J, An W
Nucleic Acids Res
. 2010 Nov;
39(3):e16.
PMID: 21071410
Recent studies employing genome-wide approaches have provided an unprecedented view of the scope of L1 activities on structural variations in the human genome, and further reinforced the role of L1s...
8.
Rosser J, An W
Gene
. 2010 Feb;
456(1-2):15-23.
PMID: 20167267
Recent transgenic studies on L1 retrotransposons have afforded exciting insights into L1 biology, and a unique opportunity to model their function and regulation in vivo. Thus far, the majority of...