James M Kasper
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Explore the profile of James M Kasper including associated specialties, affiliations and a list of published articles.
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12
Citations
95
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Recent Articles
1.
The neuroanatomical organization of the hypothalamus is driven by spatial and topological efficiency
Smith N, Ameen S, Miller S, Kasper J, Schwarz J, Hommel J, et al.
Front Syst Neurosci
. 2024 Aug;
18:1417346.
PMID: 39165582
The hypothalamus in the mammalian brain is responsible for regulating functions associated with survival and reproduction representing a complex set of highly interconnected, yet anatomically and functionally distinct, sub-regions. It...
2.
Kasper J, Smith A, Miller S, Ara , Russell W, Cunningham K, et al.
Neuropsychopharmacology
. 2021 Dec;
47(11):1875-1882.
PMID: 34916591
The nucleus accumbens shell (NAcSh) and its afferent and efferent neuronal projections control key aspects of motivation for cocaine. A recently described regulator of γ-aminobutyric acid (GABA) projections from the...
3.
Smith A, Ogunseye K, DeBenedictis J, Peris J, Kasper J, Hommel J
Sci Rep
. 2020 Dec;
10(1):22093.
PMID: 33328492
Food intake is a complex behavior regulated by discrete brain nuclei that integrate homeostatic nutritional requirements with the hedonic properties of food. Homeostatic feeding (i.e. titration of caloric intake), is...
4.
Venkannagari H, Kasper J, Misra A, Rush S, Fan S, Lee H, et al.
J Mol Biol
. 2020 Jul;
432(19):5287-5303.
PMID: 32710982
Neuronal growth regulator 1 (NEGR1) and neurotrimin (NTM) are abundant cell-surface proteins found in the brain and form part of the IgLON (Immunoglobulin LSAMP, OBCAM, Neurotrimin) family. In humans, NEGR1...
5.
Smith A, Kasper J, Anastasio N, Hommel J
Nutrients
. 2019 Feb;
11(2).
PMID: 30717427
Binge-eating disorder (BED) is the most common eating disorder, characterized by rapid, recurrent overconsumption of highly palatable food in a short time frame. BED shares an overlapping behavioral phenotype with...
6.
Kasper J, Smith A, Hommel J
Front Behav Neurosci
. 2018 Nov;
12:271.
PMID: 30483076
Cocaine use disorder (CUD) is characterized by repeated cycles of drug seeking and drug taking. Currently, there are no available pharmacotherapies to treat CUD, partially due to a lack of...
7.
McCue D, Kasper J, Ara , Hommel J
Behav Brain Res
. 2018 Sep;
359:763-770.
PMID: 30227148
A diet of energy-dense food, characterized mainly as a high-fat diet, leads to a persistent excessive consumption defined as overeating. According to the National Institute of Health, more than 2...
8.
Sampson C, Kasper J, Felsing D, Raval S, Ye N, Wang P, et al.
Pharmacol Res Perspect
. 2018 Aug;
6(5):e00425.
PMID: 30151213
Obesity is a growing public health concern, with 37.5% of the adult population in need of therapeutics that are more efficacious with a better side effect profile. An innovative target...
9.
Scala F, Nenov M, Crofton E, Singh A, Folorunso O, Zhang Y, et al.
Cell Rep
. 2018 Apr;
23(2):555-567.
PMID: 29642012
Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na channel Nav1.6...
10.
Kasper J, McCue D, Milton A, Szwed A, Sampson C, Huang M, et al.
Biol Psychiatry
. 2016 Apr;
80(11):878-887.
PMID: 27105831
Background: Neuromedin U (NMU) is a neuropeptide enriched in the nucleus accumbens shell (NAcSh), a brain region associated with reward. While NMU and its receptor, NMU receptor 2 (NMUR2), have...