James M Fadool
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Explore the profile of James M Fadool including associated specialties, affiliations and a list of published articles.
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25
Citations
784
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Recent Articles
1.
Kolling L, Tatti R, Lowry T, Loeven A, Fadool J, Fadool D
J Neurosci
. 2022 Jun;
42(30):5966-5990.
PMID: 35710623
Metabolic state can alter olfactory sensitivity, but it is unknown whether the activity of the olfactory bulb (OB) may fine tune metabolic homeostasis. Our objective was to use CRISPR gene...
2.
Zelinka C, Sotolongo-Lopez M, Fadool J
Mol Vis
. 2018 Sep;
24:587-602.
PMID: 30210230
Purpose: Retinitis pigmentosa (RP) is a collection of genetic disorders that results in the degeneration of light-sensitive photoreceptor cells, leading to blindness. RP is associated with more than 70 loci...
3.
Fadool J, Linser P
Rouxs Arch Dev Biol
. 2017 Mar;
203(6):328-339.
PMID: 28305826
The 5AII/HT7 antigen is the avian homologue of a 45-50X10 M plasma membrane glycoprotein of the immunoglobulin super-gene family also identified in mammalian species (basigin, mouse gp42, MRC OX-47 antigen,...
4.
Kovach C, Al Koborssy D, Huang Z, Chelette B, Fadool J, Fadool D
Front Physiol
. 2016 Jun;
7:178.
PMID: 27242550
Gene-targeted deletion of the potassium channel Kv1.3 (Kv1.3(-∕-)) results in "Super-smeller" mice with a sensory phenotype that includes an increased olfactory ability linked to changes in olfactory circuitry, increased abundance...
5.
Sotolongo-Lopez M, Alvarez-Delfin K, Saade C, Vera D, Fadool J
PLoS Genet
. 2016 Apr;
12(4):e1005968.
PMID: 27058886
The visual system of a particular species is highly adapted to convey detailed ecological and behavioral information essential for survival. The consequences of structural mutations of opsins upon spectral sensitivity...
6.
Taylor S, Alvarez-Delfin K, Saade C, Thomas J, Thummel R, Fadool J, et al.
Invest Ophthalmol Vis Sci
. 2015 Nov;
56(12):7496-515.
PMID: 26580854
Purpose: Photoreceptor genesis in the retina requires precise regulation of progenitor cell competence, cell cycle exit, and differentiation, although information around the mechanisms that govern these events currently is lacking....
7.
Yoshimatsu T, Williams P, DOrazi F, Suzuki S, Fadool J, Allison W, et al.
Nat Commun
. 2014 May;
5:3699.
PMID: 24832361
Many neurons receive synapses in stereotypic proportions from converging but functionally distinct afferents. However, developmental mechanisms regulating synaptic convergence are not well understood. Here we describe a heterotypic mechanism by...
8.
Saade C, Alvarez-Delfin K, Fadool J
J Neurosci
. 2013 Feb;
33(5):1804-14.
PMID: 23365220
Humans are largely dependent upon cone-mediated vision. However, death or dysfunction of rods, the predominant photoreceptor subtype, results in secondary loss of cones, remodeling of retinal circuitry, and blindness. The...
9.
Morris A, Forbes-Osborne M, Pillai L, Fadool J
Invest Ophthalmol Vis Sci
. 2011 Jan;
52(5):2255-66.
PMID: 21217106
Purpose: XOPS-mCFP transgenic zebrafish experience a continual cycle of rod photoreceptor development and degeneration throughout life, making them a useful model for investigating the molecular determinants of rod photoreceptor regeneration....
10.
Perkins B, Fadool J
Methods Cell Biol
. 2010 Nov;
100:205-18.
PMID: 21111218
In recent years, studies of zebrafish rod and cone photoreceptors have yielded novel insights into the differentiation of distinct photoreceptor cell types and the mechanisms guiding photoreceptor regeneration following cell...