Brian D Perkins
Overview
Explore the profile of Brian D Perkins including associated specialties, affiliations and a list of published articles.
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Articles
44
Citations
761
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Recent Articles
1.
Song P, Parsana D, Singh R, Pollock L, Anand-Apte B, Perkins B
Sci Rep
. 2024 Aug;
14(1):20146.
PMID: 39209978
Microglia are resident immune cells in the central nervous system, including the retina that surveil the environment for damage and infection. Following retinal damage, microglia undergo morphological changes, migrate to...
2.
Perkins B, Lobo G, Kondkar A, Millan J
Front Cell Dev Biol
. 2023 Oct;
11:1301279.
PMID: 37860821
No abstract available.
3.
Grabinski S, Parsana D, Perkins B
Front Mol Neurosci
. 2023 Jun;
16:1148840.
PMID: 37293546
Acute injury to the adult zebrafish retina triggers the release of pro-inflammatory cytokines and growth factors that stimulate multiple gene regulatory networks, which ultimately stimulate Müller glia to proliferate and...
4.
Perkins B
J Transl Genet Genom
. 2022 Jun;
6(1):95-110.
PMID: 35693295
Inherited retinal degenerations (IRDs) cause permanent vision impairment or vision loss due to the death of rod and cone photoreceptors. Animal models of IRDs have been instrumental in providing knowledge...
5.
Fogerty J, Song P, Boyd P, Grabinski S, Hoang T, Reich A, et al.
J Neurosci
. 2022 Jun;
42(26):5144-5158.
PMID: 35672150
Photoreceptor degeneration leads to irreversible vision loss in humans with retinal dystrophies such as retinitis pigmentosa. Whereas photoreceptor loss is permanent in mammals, zebrafish possesses the ability to regenerate retinal...
6.
Banerjee S, Ranspach L, Luo X, Cianciolo L, Fogerty J, Perkins B, et al.
Sci Rep
. 2022 Mar;
12(1):3511.
PMID: 35241734
Genetic Leukoencephalopathies (gLEs) are heritable white matter disorders that cause progressive neurological abnormalities. A founder mutation in the human endolysosomal trafficking protein VPS11 has been identified in Ashkenazi Jewish patients...
7.
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo W, et al.
Science
. 2021 Dec;
374(6573):eabk0410.
PMID: 34882480
Cytokinetic membrane abscission is a spatially and temporally regulated process that requires ESCRT (endosomal sorting complexes required for transport)–dependent control of membrane remodeling at the midbody, a subcellular organelle that...
8.
Ashery-Padan R, Perkins B, Conte I
Front Cell Dev Biol
. 2021 Aug;
9:737703.
PMID: 34395454
No abstract available.
9.
Fogerty J, Perkins B
Stem Cell Res
. 2021 Feb;
52:102243.
PMID: 33626495
CEP290 is a principal component of the primary cilium and is important for the proper function of ciliated cells. CEP290 mutations have been linked to numerous ciliopathies, with a wide...
10.
Song P, Fogerty J, Cianciolo L, Stupay R, Perkins B
Front Cell Dev Biol
. 2020 Dec;
8:578528.
PMID: 33324636
Bardet-Biedl syndrome (BBS) is a heterogeneous and pleiotropic autosomal recessive disorder characterized by obesity, retinal degeneration, polydactyly, renal dysfunction, and mental retardation. BBS results from defects in primary and sensory...