James M Chell
Overview
Explore the profile of James M Chell including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
354
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Recent Articles
1.
Bell A, Mitchell J, Kiemen A, Lyman M, Fujikura K, Lee J, et al.
Cell Syst
. 2024 Aug;
15(8):753-769.e5.
PMID: 39116880
This study introduces a new imaging, spatial transcriptomics (ST), and single-cell RNA-sequencing integration pipeline to characterize neoplastic cell state transitions during tumorigenesis. We applied a semi-supervised analysis pipeline to examine...
2.
Llorens-Bobadilla E, Chell J, Le Merre P, Wu Y, Zamboni M, Bergenstrahle J, et al.
Science
. 2020 Oct;
370(6512).
PMID: 33004487
Injuries to the central nervous system (CNS) are inefficiently repaired. Resident neural stem cells manifest a limited contribution to cell replacement. We have uncovered a latent potential in neural stem...
3.
Chell J, Frisen J
Cell Stem Cell
. 2012 Sep;
11(3):282-4.
PMID: 22958925
Recently in Nature, Song et al. (2012) show that the neurotransmitter GABA acts directly on radial glia-like neural stem cells to maintain quiescence and provide a mechanism for how neuronal...
4.
Chell J, Brand A
Cell
. 2010 Dec;
143(7):1161-73.
PMID: 21183078
The systemic regulation of stem cells ensures that they meet the needs of the organism during growth and in response to injury. A key point of regulation is the decision...
5.
Chell J, Brand A
Cell
. 2008 May;
133(5):769-71.
PMID: 18510921
During development, many neural stem cells "age" as they sequentially generate distinct neuronal or glial cell types. In this issue, Maurange et al. (2008) now identify the temporal control factors...
6.
Egger B, Chell J, Brand A
Philos Trans R Soc Lond B Biol Sci
. 2007 Feb;
363(1489):39-56.
PMID: 17309865
Drosophila neuroblasts are similar to mammalian neural stem cells in their ability to self-renew and to produce many different types of neurons and glial cells. In the past two decades,...