James L Kreindler
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Explore the profile of James L Kreindler including associated specialties, affiliations and a list of published articles.
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48
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2396
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Recent Articles
1.
Emson C, Han J, Hopkins C, Asimus S, Cann J, Chain D, et al.
Br J Clin Pharmacol
. 2024 May;
90(8):1952-1963.
PMID: 38715387
Aims: Benralizumab, a humanized, afucosylated monoclonal antibody against the interleukin 5 receptor, α subunit, causes rapid depletion of eosinophils by antibody-dependent cellular cytotoxicity. We investigated the pharmacokinetic and pharmacodynamic effects...
2.
3.
Peters A, Bengtson L, Chung Y, Emmanuel B, Katial R, Kreindler J, et al.
Allergy Asthma Proc
. 2022 Sep;
43(5):435-445.
PMID: 36065104
Limited data exist on the clinical and economic burden of chronic rhinosinusitis with nasal polyposis (CRSwNP). To describe patient characteristics, health-care resource utilization (HCRU), and health-care costs among patients with...
4.
Davis G, Zeiger R, Emmanuel B, Chung Y, Tran T, Evans K, et al.
Clin Ther
. 2022 Sep;
44(9):1187-1202.
PMID: 36057475
Purpose: Nasal polyps (NPs) develop in 20% to 30% of patients with chronic rhinosinusitis. Severe forms of chronic rhinosinusitis with nasal polyposis (CRSwNP) may be treated with systemic corticosteroids (SCSs),...
5.
Bachert C, Han J, Desrosiers M, Gevaert P, Heffler E, Hopkins C, et al.
J Allergy Clin Immunol
. 2021 Oct;
149(4):1309-1317.e12.
PMID: 34599979
Background: Eosinophilic inflammation has been implicated in the pathogenesis, severity, and treatment responsiveness of chronic rhinosinusitis with nasal polyps (CRSwNP). Objective: We sought to assess the efficacy and safety of...
6.
Panettieri Jr R, Chipps B, Moore W, Soong W, Carr W, Kreindler J, et al.
J Asthma
. 2021 Aug;
59(9):1859-1868.
PMID: 34374622
Objective: For patients with severe asthma (SA), overestimation of asthma control may lead to poorer outcomes. The objective of this study was to assess concurrent patient and specialist assessments of...
7.
Ludbrook V, Hanrott K, Kreindler J, Marks-Konczalik J, Bird N, Hewens D, et al.
ERJ Open Res
. 2021 Aug;
7(3).
PMID: 34350286
Objective: Airway sensory nerves involved in the cough reflex are activated by adenosine triphosphate (ATP) agonism of P2X purinoceptor 3 (P2X3) receptors. Transient receptor potential vanilloid 4 (TRPV4) channel activation...
8.
Most J, Ambrose C, Chung Y, Kreindler J, Near A, Brunton S, et al.
J Allergy Clin Immunol Pract
. 2021 Jun;
9(10):3662-3671.e1.
PMID: 34148858
Background: U.S. guidelines recommend that patients with severe asthma be referred to specialists (allergists/immunologists or pulmonologists) for systematic assessment or comanagement; however, contemporary, real-world data on the frequency and impact...
9.
Hegewald M, Horne B, Trudo F, Kreindler J, Chung Y, Rea S, et al.
Int J Chron Obstruct Pulmon Dis
. 2020 Oct;
15:2629-2641.
PMID: 33122901
Purpose: This retrospective, observational cohort study investigated the association of blood eosinophil counts within 1 week of hospitalization for acute exacerbation of COPD (AECOPD) with subsequent risk of all-cause and...
10.
Zeiger R, Sullivan P, Chung Y, Kreindler J, Zimmerman N, Tkacz J
J Allergy Clin Immunol Pract
. 2020 Jul;
8(10):3455-3465.e13.
PMID: 32679349
Background: Systemic corticosteroids (SCS) may cause complications for patients with asthma. Objective: We sought to better understand the burden of SCS use in persistent asthma, including health care costs. Methods:...