James L Daniel
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Explore the profile of James L Daniel including associated specialties, affiliations and a list of published articles.
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17
Citations
364
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Recent Articles
1.
Chen X, Ren L, Kim S, Carpino N, Daniel J, Kunapuli S, et al.
J Biol Chem
. 2010 Jul;
285(41):31268-76.
PMID: 20670933
TULA-1 (UBASH3A/STS-2) and TULA-2 (p70/STS-1) represent a novel class of protein-tyrosine phosphatases. Previous studies suggest that TULA-2 is sequence-selective toward phosphotyrosyl (Tyr(P)) peptides. In this work the substrate specificity of...
2.
Thomas D, Getz T, Newman T, Dangelmaier C, Carpino N, Kunapuli S, et al.
Blood
. 2010 Jun;
116(14):2570-8.
PMID: 20585042
T-cell ubiquitin ligand-2 (TULA-2) is a recently discovered histidine tyrosine phosphatase thought to be ubiquitously expressed. In this work, we have investigated whether TULA-2 has a key role in platelet...
3.
Daniel J, Dangelmaier C, Mada S, Buitrago L, Jin J, Langdon W, et al.
J Biol Chem
. 2010 Apr;
285(23):17282-91.
PMID: 20400514
Cbl-b, a member of the Cbl family of E3 ubiquitin ligases, plays an important role in the activation of lymphocytes. However, its function in platelets remains unknown. We show that...
4.
Mayanglambam A, Dangelmaier C, Thomas D, Reddy C, Daniel J, Kunapuli S
Platelets
. 2010 Feb;
21(3):211-20.
PMID: 20158382
Turmeric (Curcuma longa), a herbal remedy and culinary spice, has been used in traditional Indian culture for millennia. An active ingredient found in turmeric is curcumin (diferuloylmethane). In the current...
5.
Kim S, Mangin P, Dangelmaier C, Lillian R, Jackson S, Daniel J, et al.
J Biol Chem
. 2009 Aug;
284(49):33763-72.
PMID: 19700402
Glycoprotein (GP) VI is a critical platelet collagen receptor. Phosphoinositide 3-kinase (PI3K) plays an important role in GPVI-mediated platelet activation, yet the major PI3K isoforms involved in this process have...
6.
Chari R, Kim S, Murugappan S, Sanjay A, Daniel J, Kunapuli S
Blood
. 2009 Jul;
114(14):3056-63.
PMID: 19587372
Protein kinase C-delta (PKC-delta) is expressed in platelets and activated downstream of protease-activated receptors (PARs) and glycoprotein VI (GPVI) receptors. We have previously shown that PKC-delta positively regulates PAR-mediated dense...
7.
Mao Y, Jin J, Daniel J, Kunapuli S
Platelets
. 2009 May;
20(3):191-8.
PMID: 19437337
Plasmin, a major extracellular protease, activates platelets through PAR4 receptors. Plasmin-induced full aggregation is achieved at lower concentrations (0.1 U/mL) in murine platelets as compared to human platelets (1 U/mL)....
8.
Jin J, Mao Y, Thomas D, Kim S, Daniel J, Kunapuli S
Biochem Pharmacol
. 2008 Dec;
77(5):835-44.
PMID: 19073150
Platelet secretion is an important physiological event in hemostasis. The protease-activated receptors, PAR 1 and PAR 4, and the thromboxane receptor activate the G(12/13) pathways, in addition to the G(q)...
9.
Bhavaraju K, Kim S, Daniel J, Kunapuli S
Eur J Pharmacol
. 2007 Dec;
580(3):285-90.
PMID: 18068154
In the present study, we characterized OXSI-2 [3-(1-Methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide], a putative inhibitor of Syk, and determined its specificity and selectivity in platelets. We found that OXSI-2 completely abolished convulxin-induced platelet...
10.
Kahner B, Dorsam R, Mada S, Kim S, Stalker T, Brass L, et al.
Blood
. 2007 Jun;
110(7):2449-56.
PMID: 17579181
Collagen activates platelets through an intracellular signaling cascade downstream of glycoprotein VI (GPVI). We have investigated the contribution of hematopoietic lineage cell-specific protein 1 (HS1) downstream of GPVI in platelet...