James J H Chong
Overview
Explore the profile of James J H Chong including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
1558
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Recent Articles
21.
Selvakumar D, Wilkie E, Deshmukh T, Ravindran D, Kotake Y, Lu J, et al.
J Vis Exp
. 2023 Feb;
(192).
PMID: 36847388
Myocardial infarction is one of the leading causes of death and disability worldwide, and there is an urgent need for novel cardioprotective or regenerative strategies. An essential component of drug...
22.
Kazi S, von Huben A, Marschner S, Chong J, Denniss A, Ong A, et al.
Heart Lung Circ
. 2023 Feb;
32(4):480-486.
PMID: 36801127
Background: Recent studies suggest that the risk factor profile of patients presenting with ST elevation myocardial infarction (STEMI) is changing. Aim: The aim is to determine if there has been...
23.
Hume R, Kanagalingam S, Deshmukh T, Chen S, Mithieux S, Rashid F, et al.
Circ Res
. 2022 Dec;
132(1):72-86.
PMID: 36453283
Background: Myocardial infarction (MI) is among the leading causes of death worldwide. Following MI, necrotic cardiomyocytes are replaced by a stiff collagen-rich scar. Compared to collagen, the extracellular matrix protein...
24.
Leung H, Perdomo J, Ahmadi Z, Zheng S, Rashid F, Enjeti A, et al.
Nat Commun
. 2022 Sep;
13(1):5206.
PMID: 36064843
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.COV2.S (Janssen) against COVID-19. The mechanisms involved in clot...
25.
Farraha M, Rao R, Igoor S, Le T, Barry M, Davey C, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012498
Sinoatrial node dysfunction can manifest as bradycardia, leading to symptoms of syncope and sudden cardiac death. Electronic pacemakers are the current standard of care but are limited due to a...
26.
Rao R, Farraha M, Logan G, Igoor S, Kok C, Chong J, et al.
Viruses
. 2022 Jul;
14(8).
PMID: 35893689
Gene therapy is making significant impact on a modest, yet growing, number of human diseases. Justifiably, the preferred viral vector for clinical use is that based on recombinant adeno-associated virus...
27.
Drak D, Fulcher J, Kilian J, Chong J, Grover R, Sindone A, et al.
Intern Med J
. 2022 Jun;
53(9):1595-1601.
PMID: 35666643
Background: Heart failure is a major burden in Australia in terms of morbidity, mortality and healthcare expenditure. Multiple evidence-based therapies are recommended for heart failure with reduced ejection fraction (HFrEF),...
28.
Selvakumar D, Reyes L, Chong J
Curr Cardiol Rep
. 2022 Mar;
24(5):445-461.
PMID: 35275365
Purpose Of Review: Exciting pre-clinical data presents pluripotent stem cell-derived cardiomyocytes (PSC-CM) as a novel therapeutic prospect following myocardial infarction, and worldwide clinical trials are imminent. However, despite notable advances,...
29.
Selvakumar D, Deshmukh T, Foster S, Sanaei N, Min A, Grieve S, et al.
Sci Rep
. 2022 Mar;
12(1):3727.
PMID: 35260600
Breath-held (BH) cardiac magnetic resonance imaging (CMR) is the gold standard for volumetric quantification. However, large animals for pre-clinical research are unable to voluntarily breath-hold, necessitating general anaesthesia and mechanical...
30.
Thavapalachandran S, Le T, Romanazzo S, Rashid F, Ogawa M, Kilian K, et al.
Cytotherapy
. 2021 Sep;
23(12):1074-1084.
PMID: 34588150
Background Aims: Mesenchymal stromal cells (MSCs) have been shown to improve cardiac function after injury and are the subject of ongoing clinical trials. In this study, the authors tested the...