Richard P Harvey
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Explore the profile of Richard P Harvey including associated specialties, affiliations and a list of published articles.
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165
Citations
7537
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Recent Articles
1.
Cartland S, Patil M, Kelland E, Le N, Boccanfuso L, Stanley C, et al.
Sci Adv
. 2024 Oct;
10(40):eadn8760.
PMID: 39365855
Reversal of ischemia is mediated by neo-angiogenesis requiring endothelial cell (EC) and pericyte interactions to form stable microvascular networks. We describe an unrecognized role for tumor necrosis factor-related apoptosis-inducing ligand...
2.
Hilton D, OMalley B, Cole A, Harvey R, Dunwoodie S, Sholler G, et al.
Cardiol Young
. 2024 Sep;
34(8):1645-1652.
PMID: 39323354
Introduction: The cause of most CHD is unknown and considered complex, implicating genetic and environmental factors in disease causation. The Kids Heart BioBank was established in 2003 to accelerate genetic...
3.
Patrick R, Janbandhu V, Tallapragada V, Tan S, McKinna E, Contreras O, et al.
Sci Adv
. 2024 Jun;
10(25):eadk8501.
PMID: 38905342
Single-cell technology has allowed researchers to probe tissue complexity and dynamics at unprecedented depth in health and disease. However, the generation of high-dimensionality single-cell atlases and virtual three-dimensional tissues requires...
4.
Janbandhu V, Tallapragada V, Li J, Shewale B, Ghazanfar S, Patrick R, et al.
Circulation
. 2024 Jun;
149(24):1931-1934.
PMID: 38857329
No abstract available.
5.
Filipe E, Velayuthar S, Philp A, Nobis M, Latham S, Parker A, et al.
Adv Sci (Weinh)
. 2024 Apr;
11(23):e2307963.
PMID: 38602451
In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter...
6.
Hardy S, Liesinger L, Patrick R, Poettler M, Rech L, Gindlhuber J, et al.
JACC Basic Transl Sci
. 2024 Jan;
8(12):1539-1554.
PMID: 38205347
Irreversible fibrosis is a hallmark of myocardial infarction (MI) and heart failure. Extracellular matrix protein-1 (ECM-1) is up-regulated in these hearts, localized to fibrotic, inflammatory, and perivascular areas. ECM-1 originates...
7.
Friedman C, Cheetham S, Negi S, Mills R, Ogawa M, Redd M, et al.
Dev Cell
. 2023 Dec;
59(1):91-107.e6.
PMID: 38091997
Genomic regulation of cardiomyocyte differentiation is central to heart development and function. This study uses genetic loss-of-function human-induced pluripotent stem cell-derived cardiomyocytes to evaluate the genomic regulatory basis of the...
8.
Murtha L, Hardy S, Mabotuwana N, Bigland M, Bailey T, Raguram K, et al.
Sci Rep
. 2023 Sep;
13(1):14995.
PMID: 37696945
Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role...
9.
Zhou Z, Ma X, Lin Y, Cheng D, Bavi N, Secker G, et al.
Science
. 2023 Aug;
381(6659):799-804.
PMID: 37590348
Piezo channels are critical cellular sensors of mechanical forces. Despite their large size, ubiquitous expression, and irreplaceable roles in an ever-growing list of physiological processes, few Piezo channel-binding proteins have...
10.
Thorpe J, Perry M, Contreras O, Hurley E, Parker G, Harvey R, et al.
Stem Cell Res Ther
. 2023 Jul;
14(1):183.
PMID: 37501071
Background: Atrial fibrillation is the most common arrhythmia syndrome and causes significant morbidity and mortality. Current therapeutics, however, have limited efficacy. Notably, many therapeutics shown to be efficacious in animal...