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James Hixson

Explore the profile of James Hixson including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 355
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Recent Articles
1.
Noordam R, Wang W, Nagarajan P, Wang H, Brown M, Bentley A, et al.
medRxiv . 2024 Sep; PMID: 39281768
We performed large-scale genome-wide gene-sleep interaction analyses of lipid levels to identify novel genetic variants underpinning the biomolecular pathways of sleep-associated lipid disturbances and to suggest possible druggable targets. We...
2.
Chen J, Qiu X, Avadhanula V, Shepard S, Kim D, Hixson J, et al.
Influenza Other Respir Viruses . 2021 Dec; 16(3):492-500. PMID: 34894077
Background: Human respiratory syncytial virus (RSV) is one of the leading causes of respiratory infections, especially in infants and young children. Previous RSV sequencing studies have primarily focused on partial...
3.
Hillman P, Baker C, Hebert L, Brown M, Hixson J, Ashley-Koch A, et al.
Mol Genet Genomic Med . 2020 Sep; 8(11):e1495. PMID: 32960507
Background: Neural tube defects (NTDs) are the second most common complex birth defect, yet, our understanding of the genetic contribution to their development remains incomplete. Two environmental factors associated with...
4.
Piedra F, Qiu X, Teng M, Avadhanula V, Machado A, Kim D, et al.
PLoS One . 2020 Jan; 15(1):e0227558. PMID: 31923213
Respiratory syncytial virus (RSV) is a nonsegmented negative-strand RNA virus (NSV) and a leading cause of severe lower respiratory tract illness in infants and the elderly. Transcription of the ten...
5.
Sung Y, de las Fuentes L, Winkler T, Chasman D, Bentley A, Kraja A, et al.
Hum Mol Genet . 2019 May; 28(15):2615-2633. PMID: 31127295
Elevated blood pressure (BP), a leading cause of global morbidity and mortality, is influenced by both genetic and lifestyle factors. Cigarette smoking is one such lifestyle factor. Across five ancestries,...
6.
Mao C, Howard T, Sullivan D, Fu Z, Yu G, Parker S, et al.
J Proteom Genom Res . 2018 Jan; 2(1):1-12. PMID: 29367937
Factors that contribute to the onset of atherosclerosis may be elucidated by bioinformatic techniques applied to multiple sources of genomic and proteomic data. The results of genome wide association studies,...
7.
Spracklen C, Chen P, Kim Y, Wang X, Cai H, Li S, et al.
Hum Mol Genet . 2017 Mar; 26(9):1770-1784. PMID: 28334899
Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides...
8.
Chappell C, Darkoh C, Shimmin L, Farhana N, Kim D, Okhuysen P, et al.
Infect Immun . 2016 Jun; 84(8):2299-306. PMID: 27245413
Cryptosporidium causes significant diarrhea worldwide, especially among children and immunocompromised individuals, and no effective drug treatment is currently available for those who need it most. In this report, previous volunteer...
9.
Chen G, de las Fuentes L, Gu C, He J, Gu D, Kelly T, et al.
BMC Genet . 2015 Jun; 16:64. PMID: 26088064
Background: Hypertension is a complex trait that often co-occurs with other conditions such as obesity and is affected by genetic and environmental factors. Aggregate indices such as principal components among...
10.
Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang J, et al.
Hum Mol Genet . 2014 May; 23(20):5492-504. PMID: 24861553
Recent genetic association studies have identified 55 genetic loci associated with obesity or body mass index (BMI). The vast majority, 51 loci, however, were identified in European-ancestry populations. We conducted...