James H Finigan
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Explore the profile of James H Finigan including associated specialties, affiliations and a list of published articles.
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20
Citations
524
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Recent Articles
1.
Wilson K, Kaminsky D, Michaud G, Sharma S, Nici L, Folz R, et al.
Ann Am Thorac Soc
. 2020 Jul;
17(11):1343-1351.
PMID: 32663071
In March 2020, many elective medical services were canceled in response to the coronavirus disease 2019 (COVID-19) pandemic. The daily case rate is now declining in many states and there...
2.
Kern J, Kim J, Foster D, Mishra R, Gardner E, Poirier J, et al.
J Thorac Oncol
. 2020 Jun;
15(9):1522-1534.
PMID: 32599072
Objectives: SCLC represents 15% of all lung cancer diagnoses in the United States and has a particularly poor prognosis. We hypothesized that kinases regulating SCLC survival pathways represent therapeutically targetable...
3.
Regan E, Lowe K, Make B, Lynch D, Kinney G, Budoff M, et al.
Chronic Obstr Pulm Dis
. 2019 Jul;
6(3):233-245.
PMID: 31342730
Background: Lung cancer screening (LCS) via chest computed tomography (CT) scans can save lives by identifying early-stage tumors. However, most smokers die of comorbid smoking-related diseases. LCS scans contain information...
4.
Mishra R, Foster D, Finigan J, Kern J
Biochem Biophys Res Commun
. 2019 Apr;
513(4):794-799.
PMID: 31000198
A clear understanding of the mechanisms that regulate the alveolar epithelium's barrier is critical to develop new therapeutic strategies to mitigate lung injury. The HER2/HER3 receptor tyrosine kinase complex plays...
5.
Mishra R, Foster D, Vasu V, Thaikoottathil J, Kosmider B, Chu H, et al.
Am J Respir Cell Mol Biol
. 2015 Nov;
54(6):853-64.
PMID: 26600084
The airway epithelium constitutes a protective barrier against inhaled insults, such as viruses, bacteria, and toxic fumes, including cigarette smoke (CS). Maintenance of bronchial epithelial integrity is central for airway...
6.
Berman R, Huang C, Jiang D, Finigan J, Wu Q, Chu H
J Clin Cell Immunol
. 2014 Dec;
5(5).
PMID: 25478290
Objective: MUC18 or CD146, a transmembrane glycoprotein, is mainly expressed by endothelial cells and smooth muscle cells where it serves as a cell-cell adhesion molecule. We have found MUC18 up-regulation...
7.
Finigan J, Vasu V, Thaikoottathil J, Mishra R, Shatat M, Mason R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2014 Oct;
308(2):L199-207.
PMID: 25326580
The receptor tyrosine kinase human epidermal growth factor receptor-2 (HER2) is known to regulate pulmonary epithelial barrier function; however, the mechanisms behind this effect remain unidentified. We hypothesized that HER2...
8.
Kim J, Vasu V, Mishra R, Singleton K, Yoo M, Leach S, et al.
Bioinformatics
. 2014 May;
30(17):2393-8.
PMID: 24812339
Motivation: Non-small-cell lung cancer (NSCLC) is the leading cause of cancer death in the United States. Targeted tyrosine kinase inhibitors (TKIs) directed against the epidermal growth factor receptor (EGFR) have...
9.
Finigan J, Kern J
Clin Chest Med
. 2013 Sep;
34(3):365-71.
PMID: 23993809
Lung cancer is the leading cause of cancer death for men and women. Most lung cancer cases are diagnosed at an advanced stage, when cure is no longer an option;...
10.
Finigan J, Kern J
Am J Respir Crit Care Med
. 2012 Jul;
186(1):7-8.
PMID: 22753683
No abstract available.