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James H Cormier

Explore the profile of James H Cormier including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 155
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Recent Articles
1.
Tamura T, Cormier J, Hebert D
J Biol Chem . 2011 Jun; 286(28):24906-15. PMID: 21632540
The endoplasmic reticulum (ER) quality control factor EDEM1 associates with a number of ER proteins and ER-associated degradation (ERAD) substrates; however, an understanding of its role in ERAD is unclear....
2.
Cormier J, Tamura T, Sunryd J, Hebert D
Mol Cell . 2009 Jun; 34(5):627-33. PMID: 19524542
Terminally misfolded or unassembled secretory proteins are retained in the endoplasmic reticulum (ER) and subsequently cleared by the ER-associated degradation (ERAD) pathway. The degradation of ERAD substrates involves mannose trimming...
3.
Tamura T, Cormier J, Hebert D
Trends Biochem Sci . 2008 Jun; 33(7):298-300. PMID: 18538572
Proteins that improperly mature in the endoplasmic reticulum (ER) are dislocated to the cytoplasm for proteasome-mediated destruction. A recent study provides insight into the incompletely understood processes for selection and...
4.
Zuber C, Cormier J, Guhl B, Santimaria R, Hebert D, Roth J
Proc Natl Acad Sci U S A . 2007 Mar; 104(11):4407-12. PMID: 17360537
Immature and nonnative proteins are retained in the endoplasmic reticulum (ER) by the quality control machinery. Folding-incompetent glycoproteins are eventually targeted for ER-associated protein degradation (ERAD). EDEM1 (ER degradation-enhancing alpha-mannosidase-like...
5.
Cormier J, Pearse B, Hebert D
Mol Cell . 2005 Sep; 19(6):717-9. PMID: 16168366
In this issue of Molecular Cell, Bhamidipati et al., (2005) and Kim et al., (2005), and Szathmary et al. (2005), and demonstrate that Yos9p selectively binds to aberrant glycoproteins in...