James G Shamul
Overview
Explore the profile of James G Shamul including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
135
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Recent Articles
1.
Shamul J, Wang Z, Gong H, Ou W, White A, Moniz-Garcia D, et al.
Nat Biomed Eng
. 2024 Sep;
PMID: 39304761
In vitro models of the human blood-brain barrier (BBB) are increasingly used to develop therapeutics that can cross the BBB for treating diseases of the central nervous system. Here we...
2.
Ou W, Stewart S, White A, Kwizera E, Xu J, Fang Y, et al.
Nat Commun
. 2023 Jan;
14(1):392.
PMID: 36693842
Cancer immunotherapy that deploys the host's immune system to recognize and attack tumors, is a promising strategy for cancer treatment. However, its efficacy is greatly restricted by the immunosuppressive (i.e.,...
3.
Kwizera E, Ou W, Lee S, Stewart S, Shamul J, Xu J, et al.
ACS Nano
. 2022 Oct;
16(11):19606.
PMID: 36301575
No abstract available.
4.
Kwizera E, Ou W, Lee S, Stewart S, Shamul J, Xu J, et al.
ACS Nano
. 2022 Jul;
16(7):11374-11391.
PMID: 35797466
The circulating tumor cells (CTCs, the root cause of cancer metastasis and poor cancer prognosis) are very difficult to culture for scale-up , which has hampered their use in cancer...
5.
Jiang B, White A, Ou W, Van Belleghem S, Stewart S, Shamul J, et al.
Bioact Mater
. 2022 Apr;
16:346-358.
PMID: 35386332
The conventional approach for fabricating polydimethylsiloxane (PDMS) microfluidic devices is a lengthy and inconvenient procedure and may require a clean-room microfabrication facility often not readily available. Furthermore, living cells can't...
6.
Xu J, Shamul J, Kwizera E, He X
Nanomaterials (Basel)
. 2022 Mar;
12(5).
PMID: 35269231
Mitochondria are critical subcellular organelles that produce most of the adenosine triphosphate (ATP) as the energy source for most eukaryotic cells. Moreover, recent findings show that mitochondria are not only...
7.
Rock inhibitor may compromise human induced pluripotent stem cells for cardiac differentiation in 3D
Jiang B, Ou W, Shamul J, Chen H, Van Belleghem S, Stewart S, et al.
Bioact Mater
. 2021 Nov;
9:508-522.
PMID: 34786523
Cardiomyocytes differentiated from human induced pluripotent stem cells (iPSCs) are valuable for the understanding/treatment of the deadly heart diseases and their drug screening. However, the very much needed homogeneous 3D...
8.
Xu J, Shamul J, Staten N, White A, Jiang B, He X
Small
. 2021 Jul;
17(33):e2102219.
PMID: 34260817
Human induced pluripotent stem cells (iPSCs) are ideal for developing personalized medicine. However, the spontaneous differentiation of human iPSCs under conventional 2D and 3D cultures results in significant heterogeneity and...
9.
White A, Zhang Y, Shamul J, Xu J, Kwizera E, Jiang B, et al.
Small
. 2021 Jun;
17(24):e2102868.
PMID: 34145733
No abstract available.
10.
Dumbleton J, Shamul J, Jiang B, Agarwal P, Huang H, Jia X, et al.
Cells Tissues Organs
. 2021 May;
211(3):294-303.
PMID: 34038907
Directed neural differentiation of embryonic stem cells (ESCs) has been studied extensively to improve the treatment of neurodegenerative disorders. This can be done through stromal-cell derived inducing activity (SDIA), by...