James E Korkola
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Explore the profile of James E Korkola including associated specialties, affiliations and a list of published articles.
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58
Citations
2340
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Recent Articles
21.
Watson S, Dane M, Chin K, Tatarova Z, Liu M, Liby T, et al.
Cell Syst
. 2018 Mar;
6(3):329-342.e6.
PMID: 29550255
Extrinsic signals are implicated in breast cancer resistance to HER2-targeted tyrosine kinase inhibitors (TKIs). To examine how microenvironmental signals influence resistance, we monitored TKI-treated breast cancer cell lines grown on...
22.
Jiao X, Velasco-Velazquez M, Wang M, Li Z, Rui H, Peck A, et al.
Cancer Res
. 2018 Jan;
78(7):1657-1671.
PMID: 29358169
The functional significance of the chemokine receptor CCR5 in human breast cancer epithelial cells is poorly understood. Here, we report that CCR5 expression in human breast cancer correlates with poor...
23.
Keenan A, Jenkins S, Jagodnik K, Koplev S, He E, Torre D, et al.
Cell Syst
. 2017 Dec;
6(1):13-24.
PMID: 29199020
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program that catalogs how human cells globally respond to chemical, genetic, and disease perturbations. Resources generated by...
24.
Hafner M, Heiser L, Williams E, Niepel M, Wang N, Korkola J, et al.
Sci Data
. 2017 Nov;
4:170166.
PMID: 29112189
Traditional means for scoring the effects of anti-cancer drugs on the growth and survival of cell lines is based on relative cell number in drug-treated and control samples and is...
25.
Korkola J, Collisson E, Heiser L, Oates C, Bayani N, Itani S, et al.
PLoS One
. 2017 Oct;
12(10):e0186551.
PMID: 29020035
[This corrects the article DOI: 10.1371/journal.pone.0133219.].
26.
Hu Z, Mao J, Curtis C, Huang G, Gu S, Heiser L, et al.
Breast Cancer Res
. 2017 Feb;
19(1):17.
PMID: 28183333
No abstract available.
27.
Hill S, Nesser N, Johnson-Camacho K, Jeffress M, Johnson A, Boniface C, et al.
Cell Syst
. 2016 Dec;
4(1):73-83.e10.
PMID: 28017544
Signaling networks downstream of receptor tyrosine kinases are among the most extensively studied biological networks, but new approaches are needed to elucidate causal relationships between network components and understand how...
28.
Hu Z, Mao J, Curtis C, Huang G, Gu S, Heiser L, et al.
Breast Cancer Res
. 2016 Jul;
18(1):70.
PMID: 27368372
Background: High mitotic activity is associated with the genesis and progression of many cancers. Small molecule inhibitors of mitotic apparatus proteins are now being developed and evaluated clinically as anticancer...
29.
Coleman D, Van Hook K, King C, Schwartzman J, Lisac R, Urrutia J, et al.
Oncotarget
. 2016 Jun;
7(26):40690-40703.
PMID: 27276681
Prostate cancer is the most commonly diagnosed and second-most lethal cancer among men in the United States. The vast majority of prostate cancer deaths are due to castration-resistant prostate cancer...
30.
Kushwaha R, Jagadish N, Kustagi M, Mendiratta G, Seandel M, Soni R, et al.
Stem Cell Reports
. 2016 May;
6(5):772-783.
PMID: 27132888
Human male germ cell tumors (GCTs) are derived from primordial germ cells (PGCs). The master pluripotency regulator and neuroectodermal lineage effector transcription factor SOX2 is repressed in PGCs and the...