James E Kirby
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Explore the profile of James E Kirby including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Huang Y, Chiaraviglio L, Bode-Sojobi I, Kirby J
Antimicrob Agents Chemother
. 2025 Mar;
:e0182824.
PMID: 40084880
Synergy of antimicrobial combinations was tested against contemporary isolates using 2D and 3D checkerboard assays. Triple combinations of omadacycline-azithromycin-clofazimine, tigecycline-azithromycin-clofazimine, omadacycline-azithromycin-linezolid, and omadacycline-azithromycin-contezolid demonstrated synergy (fractional inhibitory concentration index ≤...
2.
Gregor W, Maharjan R, Zhang Z, Chiaraviglio L, Sastry N, Cui M, et al.
mBio
. 2025 Mar;
:e0382624.
PMID: 40042268
Importance: Here, we report the cryo-electron microscopy structure of the MexY multidrug efflux pump, posing the possibility that this pump is capable of capturing antibiotics from both the central cavity...
3.
Huang Y, Chiaraviglio L, Bode-Sojobi I, Kirby J
bioRxiv
. 2025 Feb;
PMID: 39990351
Synergy of antimicrobial combinations was tested against contemporary abscessus isolates using 2-D and 3-D checkerboard assays. Triple combinations of omadacycline-azithromycin-clofazimine, tigecycline-azithromycin-clofazimine, omadacycline-azithromycin-linezolid and omadacycline-azithromycin-contezolid demonstrated synergy (FIC ≤ 0.5) against...
4.
Kang Y, Silva S, Smith K, Sumida K, Wang Y, Chiaraviglio L, et al.
Molecules
. 2025 Feb;
30(3).
PMID: 39942570
Fusidic acid is a translation inhibitor with activity against major Gram-positive bacterial pathogens such as . However, its activity against Gram-negatives is poor based on an inability to access its...
5.
Kassu M, Zulauf K, Ross J, Kirby J, Manetsch R
ACS Infect Dis
. 2024 Dec;
11(1):80-87.
PMID: 39741382
Carbapenemase producing (CPEs) represent a group of multidrug resistant pathogens for which few, if any, therapeutics options remain available. CPEs generally harbor plasmids that encode resistance to last resort carbapenems...
6.
Kanki P, Hamel D, Riedel S, Dutta S, Cheng A, Chang C, et al.
Diagn Microbiol Infect Dis
. 2024 Apr;
109(3):116282.
PMID: 38663335
The effect of freeze-thaw on SARS-CoV-2 viral viability is not well established. We isolated virus from 31 split clinical samples cultured fresh or after a 7- or 17/18-day freeze. We...
7.
Theel E, Kirby J, Pollock N
Clin Microbiol Rev
. 2024 Mar;
37(2):e0007223.
PMID: 38488364
SUMMARYThe emergence and worldwide dissemination of SARS-CoV-2 required both urgent development of new diagnostic tests and expansion of diagnostic testing capacity on an unprecedented scale. The rapid evolution of technologies...
8.
Kirmaier A, Blackshear L, Lee M, Kirby J
Diagn Microbiol Infect Dis
. 2024 Jan;
108(4):116189.
PMID: 38278004
Streptococcus iniae is a fish pathogen that can also infect mammals including dolphins and humans. Its prevalence in farmed fish, particularly tilapia, provides potential for zoonotic infections, as documented by...
9.
Reimche J, Pham C, Joseph S, Hutton S, Cartee J, Ruan Y, et al.
Lancet Infect Dis
. 2024 Jan;
24(3):e149-e151.
PMID: 38215769
No abstract available.
10.
Matysiak C, Cheng A, Kirby J
Pract Lab Med
. 2023 Sep;
36:e00332.
PMID: 37705589
Objectives: The sexually transmitted infections, (CT), (NG), (TV), and (MG), have similar risk factors and symptoms, supporting use of a quadruplex test as an efficient diagnostic modality.We assessed the clinical...