James E D Thaventhiran
Overview
Explore the profile of James E D Thaventhiran including associated specialties, affiliations and a list of published articles.
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26
Citations
1029
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Recent Articles
1.
Fischer K, Lulla A, So T, Pereyra-Gerber P, Raybould M, Kohler T, et al.
Nat Biotechnol
. 2024 Aug;
PMID: 39143416
Monoclonal antibodies are increasingly used to prevent and treat viral infections and are pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and plasmablasts) are an excellent source of...
2.
Takahashi M, So T, Chamberlain-Evans V, Hughes R, Yam-Puc J, Kania K, et al.
Sci Immunol
. 2024 May;
9(95):eade2094.
PMID: 38787961
Immunotherapy advances have been hindered by difficulties in tracking the behaviors of lymphocytes after antigen signaling. Here, we assessed the behavior of T cells active within tumors through the development...
3.
Mulroney T, Poyry T, Yam-Puc J, Rust M, Harvey R, Kalmar L, et al.
Nature
. 2023 Dec;
625(7993):189-194.
PMID: 38057663
In vitro-transcribed (IVT) mRNAs are modalities that can combat human disease, exemplified by their use as vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). IVT mRNAs are transfected into...
4.
Ferreira I, Lee C, Foster W, Abdullahi A, Dratva L, Tuong Z, et al.
Cell Rep
. 2023 Aug;
42(8):112991.
PMID: 37590132
Suboptimal responses to a primary vaccination course have been reported in the elderly, but there is little information regarding the impact of age on responses to booster third doses. Here,...
5.
Graziano V, Dannhorn A, Hulme H, Williamson K, Buckley H, Karim S, et al.
J Immunother Cancer
. 2023 Aug;
11(8).
PMID: 37553182
Background: The prognosis for patients with pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. It has been suggested that the adenosine pathway contributes to the ability of PDAC to evade the...
6.
Yam-Puc J, Hosseini Z, Horner E, Pereyra Gerber P, Beristain-Covarrubias N, Hughes R, et al.
Nat Commun
. 2023 Jun;
14(1):3292.
PMID: 37369658
Age-associated B cells (ABC) accumulate with age and in individuals with different immunological disorders, including cancer patients treated with immune checkpoint blockade and those with inborn errors of immunity. Here,...
7.
van der Klaauw A, Horner E, Pereyra-Gerber P, Agrawal U, Foster W, Spencer S, et al.
Nat Med
. 2023 May;
29(5):1146-1154.
PMID: 37169862
Obesity is associated with an increased risk of severe Coronavirus Disease 2019 (COVID-19) infection and mortality. COVID-19 vaccines reduce the risk of serious COVID-19 outcomes; however, their effectiveness in people...
8.
Moore S, Kronsteiner B, Longet S, Adele S, Deeks A, Liu C, et al.
Med
. 2023 Mar;
4(3):191-215.e9.
PMID: 36863347
Background: Both infection and vaccination, alone or in combination, generate antibody and T cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the maintenance of such responses-and hence...
9.
Lawless D, Lango Allen H, Thaventhiran J, Goddard S, Burren O, Robson E, et al.
J Allergy Clin Immunol
. 2023 Feb;
152(1):257-265.
PMID: 36828084
Background: Cystic fibrosis (CF) is one of the most common life-limiting autosomal-recessive disorders and is caused by genetic defects in the CF transmembrane conductance regulator (CFTR) gene. Some of the...
10.
Shields A, Faustini S, Hill H, Al-Taei S, Tanner C, Ashford F, et al.
Front Immunol
. 2022 Jun;
13:912571.
PMID: 35720400
Background: Patients with primary and secondary antibody deficiency are vulnerable to COVID-19 and demonstrate diminished responses following two-dose SARS-CoV-2 vaccine schedules. Third primary vaccinations have been deployed to enhance their...