James E Crooks
Overview
Explore the profile of James E Crooks including associated specialties, affiliations and a list of published articles.
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4
Citations
388
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Recent Articles
1.
Crooks J, Boughter C, Scott L, Adams E
Front Mol Biosci
. 2018 Nov;
5:95.
PMID: 30483515
CD4 and CD8 αβ T cell antigen recognition is determined by the interaction between the TCR Complementarity Determining Region (CDR) loops and the peptide-presenting MHC complex. These T cells are...
2.
Tietjen G, Gong Z, Chen C, Vargas E, Crooks J, Cao K, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(15):E1463-72.
PMID: 24706780
Recognition of phosphatidylserine (PS) lipids exposed on the extracellular leaflet of plasma membranes is implicated in both apoptotic cell removal and immune regulation. The PS receptor T cell immunoglobulin and...
3.
Sandstrom A, Peigne C, Leger A, Crooks J, Konczak F, Gesnel M, et al.
Immunity
. 2014 Apr;
40(4):490-500.
PMID: 24703779
In humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections, including Mycobacterium tuberculosis, through recognition of small pyrophosphate containing organic molecules known as phosphoantigens (pAgs). Key to pAg-mediated activation...
4.
Lopez-Sagaseta J, Dulberger C, Crooks J, Parks C, Luoma A, McFedries A, et al.
Proc Natl Acad Sci U S A
. 2013 Apr;
110(19):E1771-8.
PMID: 23613577
Mucosal-associated invariant T (MAIT) cells are an evolutionarily conserved αβ T-cell lineage that express a semi-invariant T-cell receptor (TCR) restricted to the MHC related-1 (MR1) protein. MAIT cells are dependent...