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James E Bupp

Explore the profile of James E Bupp including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bupp J, Tanga M
J Labelled Comp Radiopharm . 2016 Apr; 59(7):291-3. PMID: 27061598
A stable isotope labelled mass spectrometry internal standard of the antibiotic doxycycline was prepared to assist in pharmacokinetic analyses. Our approach was to first N-demethylate doxycycline using a non-classical Polonovski...
2.
Wu J, Perry D, Bupp J, Jiang F, Polgar W, Toll L, et al.
Neuropharmacology . 2013 Oct; 77:193-9. PMID: 24095990
Recent genetic and pharmacological studies have implicated the α3, β4 and α5 subunits of the nicotinic acetylcholine receptor (nAChR) in dependence to nicotine and other abused drugs and nicotine withdrawal....
3.
Toll L, Pajak K, Plazinska A, Jozwiak K, Jimenez L, Kozocas J, et al.
Mol Pharmacol . 2012 Mar; 81(6):846-54. PMID: 22434858
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components....
4.
Moaddel R, Vattem Venkata S, Tanga M, Bupp J, Green C, Iyer L, et al.
Talanta . 2010 Sep; 82(5):1892-904. PMID: 20875593
A parallel chiral/achiral LC-MS/MS assay has been developed and validated to measure the plasma and urine concentrations of the enantiomers of ketamine, (R)- and (S)-Ket, in complex regional pain syndrome...
5.
Kozocas J, Bupp J, Tanga M, Pluhar J, Wainer I
J Labelled Comp Radiopharm . 2010 Mar; 53(2):68-72. PMID: 20228869
The preparation of 2',4',6'-[(3)H(3)]-(R,R)-4-methoxyfenoterol, a tritium-labeled derivative of (R,R)-4-methoxyfenoterol was demonstrated on a 15 mCi scale providing material with a specific activity of 57 Ci/mmol.