James E Barrett
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Explore the profile of James E Barrett including associated specialties, affiliations and a list of published articles.
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68
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1159
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Recent Articles
21.
Inan S, Chen X, Eisenstein E, Meissler J, Geller E, Tallarida C, et al.
Life Sci
. 2021 Oct;
285:120014.
PMID: 34619167
Aims: We have shown that chemokines injected into the periaqueductal gray region of the brain blocks opioid-induced analgesia in the rat cold-water tail flick test (CWTF). The present experiments tested...
22.
Zanisi L, Floyd C, Barrett J, Bunce C, Frohmaier C, Shankar F, et al.
J Hypertens
. 2020 Jul;
38(11):2318-2324.
PMID: 32618898
Objectives: To assess the impact of variable drug response and measurement error on SBP control. Methods: We simulated a treat-to-target strategy for populations with different pretreatment SBP, whereby medications were...
23.
Barrett J, Cakiroglu A, Bunce C, Shah A, Denaxas S
Stat Med
. 2020 Jun;
39(19):2556-2567.
PMID: 32524641
Large-scale electronic health records (EHRs) present an opportunity to quickly identify suitable individuals in order to directly invite them to participate in an observational study. EHRs can contain data from...
24.
Zhang L, Hu X, Yu T, Chen Z, Dohl J, Li X, et al.
J Psychiatr Res
. 2020 Jan;
122:48-53.
PMID: 31927265
Post-traumatic stress disorder (PTSD) is a debilitating mental disorder with a prevalence of more than 7% in the US population and 12% in the military. An interaction of childhood trauma...
25.
Barber P, Weitsman G, Lawler K, Barrett J, Rowley M, Rodriguez-Justo M, et al.
J Natl Cancer Inst
. 2019 Dec;
112(9):944-954.
PMID: 31851321
Background: The phase III MRC COIN trial showed no statistically significant benefit from adding the EGFR-target cetuximab to oxaliplatin-based chemotherapy in first-line treatment of advanced colorectal cancer. This study exploits...
26.
Barrett J, Page C, Michel M
Handb Exp Pharmacol
. 2019 Dec;
260:3-16.
PMID: 31823070
It is fitting that the 100th anniversary of the Handbook of Experimental Pharmacology celebrates not only its founding but also the founding of experimental pharmacology as both had their beginnings...
27.
Geerts H, Barrett J
Front Neurosci
. 2019 Aug;
13:723.
PMID: 31379482
With the success rate of drugs for CNS indications at an all-time low, new approaches are needed to turn the tide of failed clinical trials. This paper reviews the history...
28.
Ramanathan S, Douglas S, Alexander G, Shenoda B, Barrett J, Aradillas E, et al.
J Transl Med
. 2019 Mar;
17(1):81.
PMID: 30871575
Background: Therapeutic plasma exchange (PE) or plasmapheresis is an extracorporeal procedure employed to treat immunological disorders. Exosomes, nanosized vesicles of endosomal origin, mediate intercellular communication by transferring cargo proteins and...
29.
Mei Y, Barrett J, Hu H
Cell Calcium
. 2018 Aug;
74:180-185.
PMID: 30096536
Calcium release-activated calcium (CRAC) channels are unique among ion channels that are activated in response to depletion of intracellular calcium stores and are highly permeable to Ca compared to other...
30.
Tewari S, Renney G, Brewin J, Gardner K, Kirkham F, Inusa B, et al.
Haematologica
. 2018 Mar;
103(7):1136-1142.
PMID: 29545349
Silent cerebral infarction is the most common neurological abnormality in children with sickle cell anemia, affecting 30-40% of 14 year olds. There are no known biomarkers to identify children with...