James Dachtler
Overview
Explore the profile of James Dachtler including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
394
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Recent Articles
1.
Poulter S, Lee S, Dachtler J, Wills T, Lever C
Nat Neurosci
. 2020 Dec;
24(2):266-275.
PMID: 33349710
Successfully navigating in physical or semantic space requires a neural representation of allocentric (map-based) vectors to boundaries, objects and goals. Cognitive processes such as path-planning and imagination entail the recall...
2.
Pervolaraki E, Hall S, Foresteire D, Saito T, Saido T, Whittington M, et al.
Dis Model Mech
. 2019 Aug;
12(9).
PMID: 31439589
We studied a new amyloid-beta precursor protein () knock-in mouse model of Alzheimer's disease ( ), containing the Swedish KM670/671NL mutation, the Iberian I716F mutation and the Artic E693G mutation,...
3.
Poulter S, Austen J, Kosaki Y, Dachtler J, Lever C, McGregor A
Behav Brain Res
. 2019 May;
369:111936.
PMID: 31055057
The precise role played by the hippocampus in spatial learning tasks, such as the Morris Water Maze (MWM), is not fully understood. One theory is that the hippocampus is not...
4.
Pervolaraki E, Tyson A, Pibiri F, Poulter S, Reichelt A, Rodgers R, et al.
Mol Autism
. 2019 Mar;
10:8.
PMID: 30858964
Background: Of the many genetic mutations known to increase the risk of autism spectrum disorder, a large proportion cluster upon synaptic proteins. One such family of presynaptic proteins are the...
5.
Reichelt A, Loughman A, Bernard A, Raipuria M, Abbott K, Dachtler J, et al.
Nutr Neurosci
. 2018 Nov;
23(8):613-627.
PMID: 30466372
Excessive consumption of high fat and high sugar (HFHS) diets alters reward processing, behaviour, and changes gut microbiota profiles. Previous studies in gnotobiotic mice also provide evidence that these gut...
6.
Pervolaraki E, Dachtler J, Anderson R, Holden A
Sci Rep
. 2018 Oct;
8(1):15362.
PMID: 30337648
The human heart develops through complex mechanisms producing morphological and functional changes during gestation. We have recently demonstrated using diffusion tensor MRI that over the relatively short space of 40...
7.
Pervolaraki E, Dachtler J, Anderson R, Holden A
Sci Rep
. 2017 Sep;
7(1):12272.
PMID: 28947768
The developmental timeline of the human heart remains elusive. The heart takes on its characteristic four chambered appearance by ~56 days gestational age (DGA). However, owing to the complexities (both...
8.
Dachtler J, Fox K
J Neurosci Res
. 2016 Nov;
95(1-2):518-526.
PMID: 27870449
The difference between male and female behavior and male and female susceptibility to a number of neuropsychiatric conditions is not controversial. From a biological perspective, one might expect to see...
9.
Kirshenbaum G, Idris N, Dachtler J, Roder J, Clapcote S
J Neurogenet
. 2016 Jun;
30(1):42-9.
PMID: 27276195
Social behavioral deficits have been observed in patients diagnosed with alternating hemiplegia of childhood (AHC), rapid-onset dystonia-parkinsonism and CAPOS syndrome, in which specific missense mutations in ATP1A3, encoding the Na(+),...
10.
Dachtler J, Elliott C, Rodgers R, Baillie G, Clapcote S
Sci Rep
. 2016 Jan;
6:18748.
PMID: 26728762
Disrupted-in-Schizophrenia 1 (DISC1) is a risk factor for schizophrenia and affective disorders. The full-length DISC1 protein consists of an N-terminal 'head' domain and a C-terminal tail domain that contains several...