James D Shull
Overview
Explore the profile of James D Shull including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
31
Citations
651
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Colletti 2nd J, Leland-Wavrin K, Kurz S, Hickman M, Seiler N, Samanas N, et al.
G3 (Bethesda)
. 2014 May;
4(8):1385-94.
PMID: 24875630
When treated with 17β-estradiol, female ACI rats (Rattus norvegicus) rapidly develop mammary cancers that share multiple phenotypes with luminal breast cancers. Seven distinct quantitative trait loci that harbor genetic determinants...
12.
Kurz S, Dennison K, Samanas N, Hickman M, Eckert Q, Walker T, et al.
Mamm Genome
. 2014 Jan;
25(5-6):244-52.
PMID: 24448715
Estrogens control many aspects of pituitary gland biology, including regulation of lactotroph homeostasis and synthesis and secretion of prolactin. In rat models, these actions are strain specific and heritable, and...
13.
Ding L, Zhao Y, Warren C, Sullivan R, Eliceiri K, Shull J
BMC Cancer
. 2013 Dec;
13:573.
PMID: 24304664
Background: We are using ACI and BN rats, which differ markedly in their susceptibility to 17β-estradiol (E2)-induced mammary cancer, to identify genetic variants and environmental factors that determine mammary cancer...
14.
van Heesch S, Mokry M, Boskova V, Junker W, Mehon R, Toonen P, et al.
Genome Biol
. 2013 Apr;
14(4):R33.
PMID: 23618369
Background: The ability to accurately detect DNA copy number variation in both a sensitive and quantitative manner is important in many research areas. However, genome-wide DNA copy number analyses are...
15.
Schaffer B, Leland-Wavrin K, Kurz S, Colletti J, Seiler N, Warren C, et al.
Cancer Prev Res (Phila)
. 2012 Nov;
6(1):59-69.
PMID: 23151807
The ACI rat model of 17β-estradiol (E2)-induced mammary cancer has gained wide use in the study of breast cancer etiology, prevention, and genetics. Emca8, a QTL that determines susceptibility to...
16.
Ruhlen R, Willbrand D, Besch-Williford C, Ma L, Shull J, Sauter E
Breast Cancer Res Treat
. 2008 Oct;
117(3):517-24.
PMID: 18830694
The ACI rat is a unique model of human breast cancer in that mammary cancers are induced by estrogen without carcinogens, irradiation, xenografts or transgenic manipulations. We sought to characterize...
17.
Guryev V, Saar K, Adamovic T, Verheul M, van Heesch S, Cook S, et al.
Nat Genet
. 2008 Apr;
40(5):538-45.
PMID: 18443591
The abundance and dynamics of copy number variants (CNVs) in mammalian genomes poses new challenges in the identification of their impact on natural and disease phenotypes. We used computational and...
18.
Aitman T, Critser J, Cuppen E, Dominiczak A, Fernandez-Suarez X, Flint J, et al.
Nat Genet
. 2008 Apr;
40(5):516-22.
PMID: 18443588
The rat is an important system for modeling human disease. Four years ago, the rich 150-year history of rat research was transformed by the sequencing of the rat genome, ushering...
19.
Kurz S, Hansen K, McLaughlin M, Shivaswamy V, Schaffer B, Gould K, et al.
Endocrinology
. 2008 Apr;
149(8):3850-9.
PMID: 18420736
Ept1, Ept2, Ept6, and Ept9 are quantitative trait loci mapped in crosses between the ACI and Copenhagen (COP) rat strains as genetic determinants of responsiveness of the pituitary gland to...
20.
Shull J
Breast Dis
. 2007 Dec;
28:69-86.
PMID: 18057545
The Norway rat has for many years been widely used as an experimental model for the study of breast cancer etiology and prevention. Mammary cancer can be induced in rats...