James D Potter
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Explore the profile of James D Potter including associated specialties, affiliations and a list of published articles.
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53
Citations
2038
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Recent Articles
1.
Potter J
Arch Biochem Biophys
. 2022 Jun;
726:109241.
PMID: 35667908
A stacking sodium dodecyl sulfate polyacrylamide gel electrophoresis system has been used to resolve and quantify all the major myofibrillar protein components (actin, myosin, tropomyosin, and troponin C, T, and...
2.
Chang A, Greenfield N, Singh A, Potter J, Pinto J
Front Physiol
. 2014 Dec;
5:460.
PMID: 25520664
The potential alterations to structure and associations with thin filament proteins caused by the dilated cardiomyopathy (DCM) associated tropomyosin (Tm) mutants E40K and E54K, and the hypertrophic cardiomyopathy (HCM) associated...
3.
Greaser M, Potter J, Thomas D, Strasburg G, Lehrer S, Wang C, et al.
J Muscle Res Cell Motil
. 2013 Nov;
34(5-6):441-6.
PMID: 24264290
Dr. John Gergely passed away on July 26, 2013 after a long and distinguished career. His publications spanned 67 years. He founded the Department of Muscle Research in the Retina...
4.
Wang W, Barnabei M, Asp M, Heinis F, Arden E, Davis J, et al.
Nat Med
. 2013 Feb;
19(3):305-12.
PMID: 23396207
EF-hand proteins are ubiquitous in cell signaling. Parvalbumin (Parv), the archetypal EF-hand protein, is a high-affinity Ca(2+) buffer in many biological systems. Given the centrality of Ca(2+) signaling in health...
5.
Pinto J, Gomes A, Jones M, Liang J, Nguyen S, Miller T, et al.
J Biol Chem
. 2012 Sep;
287(44):37362-70.
PMID: 22977240
Human slow skeletal troponin T (HSSTnT) shares a high degree of homology with cardiac TnT (CTnT). Although the presence of HSSTnT has not been confirmed in the heart at the...
6.
Parvatiyar M, Landstrom A, Figueiredo-Freitas C, Potter J, Ackerman M, Pinto J
J Biol Chem
. 2012 Jul;
287(38):31845-55.
PMID: 22815480
Defined as clinically unexplained hypertrophy of the left ventricle, hypertrophic cardiomyopathy (HCM) is traditionally understood as a disease of the cardiac sarcomere. Mutations in TNNC1-encoded cardiac troponin C (cTnC) are...
7.
Wang Y, Pinto J, Solis R, Dweck D, Liang J, Diaz-Perez Z, et al.
J Biol Chem
. 2011 Nov;
287(3):2156-67.
PMID: 22086914
The R21C substitution in cardiac troponin I (cTnI) is the only identified mutation within its unique N-terminal extension that is associated with hypertrophic cardiomyopathy (HCM) in man. Particularly, this mutation...
8.
Pinto J, Siegfried J, Parvatiyar M, Li D, Norton N, Jones M, et al.
J Biol Chem
. 2011 Aug;
286(39):34404-12.
PMID: 21832052
TNNC1, which encodes cardiac troponin C (cTnC), remains elusive as a dilated cardiomyopathy (DCM) gene. Here, we report the clinical, genetic, and functional characterization of four TNNC1 rare variants (Y5H,...
9.
Pinto J, Yang S, Hitz M, Parvatiyar M, Jones M, Liang J, et al.
J Biol Chem
. 2011 Apr;
286(23):20901-12.
PMID: 21502316
A novel double deletion in cardiac troponin T (cTnT) of two highly conserved amino acids (Asn-100 and Glu-101) was found in a restrictive cardiomyopathic (RCM) pediatric patient. Clinical evaluation revealed...
10.
Pinto J, Reynaldo D, Parvatiyar M, Dweck D, Liang J, Jones M, et al.
J Biol Chem
. 2010 Nov;
286(2):1005-13.
PMID: 21056975
This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca(2+) affinity of hypertrophic cardiomyopathy-cardiac troponin C (HCM-cTnC) mutants. Previously, we found that incorporation...