James C Neil
Overview
Explore the profile of James C Neil including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
893
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Recent Articles
1.
Hay J, Gilroy K, Huser C, Kilbey A, McDonald A, MacCallum A, et al.
J Cell Biochem
. 2019 Jul;
120(10):18332-18345.
PMID: 31257681
MYC and RUNX oncogenes each trigger p53-mediated failsafe responses when overexpressed in vitro and collaborate with p53 deficiency in vivo. However, together they drive rapid onset lymphoma without mutational loss...
2.
Anderson G, Mackay N, Gilroy K, Hay J, Borland G, McDonald A, et al.
J Cell Biochem
. 2017 Oct;
119(3):2750-2762.
PMID: 29052866
RUNX gene over-expression inhibits growth of primary cells but transforms cells with tumor suppressor defects, consistent with reported associations with tumor progression. In contrast, chromosomal translocations involving RUNX1 are detectable...
3.
Neil J, Hay J, Borland G
Oncotarget
. 2017 Oct;
8(38):62818-62819.
PMID: 28968950
No abstract available.
4.
Neil J, Gilroy K, Borland G, Hay J, Terry A, Kilbey A
Adv Exp Med Biol
. 2017 Mar;
962:247-264.
PMID: 28299662
The observation that the Runx genes act as targets for transcriptional activation by retroviral insertion identified a new family of dominant oncogenes. However, it is now clear that Runx genes...
5.
Terry A, Kilbey A, Naseer A, Levy L, Ahmad S, Watts C, et al.
J Virol
. 2016 Dec;
91(5).
PMID: 28031367
The human genome displays a rich fossil record of past gammaretrovirus infections, yet no current epidemic is evident, despite environmental exposure to viruses that infect human cells Feline leukemia viruses...
6.
Neil J, Borland G, Kilbey A
Aging (Albany NY)
. 2016 Oct;
8(9):1832-1833.
PMID: 27688195
No abstract available.
7.
Gilroy K, Terry A, Naseer A, de Ridder J, Allahyar A, Wang W, et al.
PLoS One
. 2016 Apr;
11(4):e0154070.
PMID: 27097319
Retroviruses have been foundational in cancer research since early studies identified proto-oncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and...
8.
Borland G, Kilbey A, Hay J, Gilroy K, Terry A, Mackay N, et al.
Oncotarget
. 2016 Apr;
7(17):22973-87.
PMID: 27056890
The Runx genes function as dominant oncogenes that collaborate potently with Myc or loss of p53 to induce lymphoma when over-expressed. Here we examined the requirement for basal Runx1 activity...
9.
Ferrari N, Riggio A, Mason S, McDonald L, King A, Higgins T, et al.
Sci Rep
. 2015 Oct;
5:15658.
PMID: 26489514
Although best known for its role in bone development and associated structures the transcription factor RUNX2 is expressed in a wide range of lineages, including those of the mammary gland....
10.
Brennan B, Weber F, Kormelink R, Schnettler E, Bouloy M, Failloux A, et al.
J Gen Virol
. 2015 Aug;
96(8):1975-1978.
PMID: 26315040
No abstract available.