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James C Delaney

Explore the profile of James C Delaney including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 1533
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Recent Articles
1.
Johnson K, Delaney J, Guillard T, Reffuveille F, Varin-Simon J, Li K, et al.
PLoS Pathog . 2023 Sep; 19(9):e1011612. PMID: 37676873
The increase in emerging drug resistant Gram-negative bacterial infections is a global concern. In addition, there is growing recognition that compromising the microbiota through the use of broad-spectrum antibiotics can...
2.
Elli S, Alekseeva A, Ramakrishnan B, Koch T, Wollacott A, Viswanathan K, et al.
Biochemistry . 2020 Oct; 59(43):4202-4211. PMID: 33085893
Bacterial infections are a growing public health threat with carbapenem-resistant being classified as a Priority 1 critical threat by the World Health Organization. Antibody-based therapeutics can serve as an alternative...
3.
Bian K, Delaney J, Zhou X, Li D
Toxics . 2019 Jun; 7(2). PMID: 31242562
As described elsewhere in this Special Issue on biomarkers, much progress has been made in the detection of modified DNA within organisms at endogenous and exogenous levels of exposure to...
4.
Touti F, Lautrette G, Johnson K, Delaney J, Wollacott A, Tissire H, et al.
Chembiochem . 2018 Jul; 19(19):2039-2044. PMID: 29984452
To combat antimicrobial infections, new active molecules are needed. Antimicrobial peptides, ever abundant in nature, are a fertile starting point to develop new antimicrobial agents but suffer from low stability,...
5.
Tang Q, Cai A, Bian K, Chen F, Delaney J, Adusumalli S, et al.
ACS Omega . 2017 Dec; 2(11):8205-8212. PMID: 29214236
Oligonucleotides serve as important tools for biological, chemical, and medical research. The preparation of oligonucleotides through automated solid-phase synthesis is well-established. However, identification of byproducts generated from DNA synthesis, especially...
6.
Tharakaraman K, Subramanian V, Viswanathan K, Sloan S, Yen H, Barnard D, et al.
Proc Natl Acad Sci U S A . 2015 Aug; 112(35):10890-5. PMID: 26283346
Emerging strains of influenza represent a significant public health threat with potential pandemic consequences. Of particular concern are the recently emerged H7N9 strains which cause pneumonia with acute respiratory distress...
7.
Fedeles B, Freudenthal B, Yau E, Singh V, Chang S, Li D, et al.
Proc Natl Acad Sci U S A . 2015 Aug; 112(33):E4571-80. PMID: 26243878
During chronic inflammation, neutrophil-secreted hypochlorous acid can damage nearby cells inducing the genomic accumulation of 5-chlorocytosine (5ClC), a known inflammation biomarker. Although 5ClC has been shown to promote epigenetic changes,...
8.
Fedeles B, Singh V, Delaney J, Li D, Essigmann J
J Biol Chem . 2015 Jul; 290(34):20734-20742. PMID: 26152727
The AlkB family of Fe(II)- and α-ketoglutarate-dependent dioxygenases is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleobases by oxidative dealkylation. The prototypical and...
9.
Chang S, Fedeles B, Wu J, Delaney J, Li D, Zhao L, et al.
Nucleic Acids Res . 2015 Apr; 43(11):5489-500. PMID: 25837992
Etheno DNA adducts are a prevalent type of DNA damage caused by vinyl chloride (VC) exposure and oxidative stress. Etheno adducts are mutagenic and may contribute to the initiation of...
10.
Hendricks G, Velazquez L, Pham S, Qaisar N, Delaney J, Viswanathan K, et al.
Antiviral Res . 2015 Feb; 116:34-44. PMID: 25637710
Heparan sulfate (HS) is a ubiquitous glycosaminoglycan that serves as a cellular attachment site for a number of significant human pathogens, including respiratory syncytial virus (RSV), human parainfluenza virus 3...