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James C Cusack Jr

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Citations 363
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Recent Articles
1.
Andric F, Al-Fairouzi A, Wettergren Y, Szeponik L, Bexe-Lindskog E, Cusack Jr J, et al.
Cancers (Basel) . 2023 Mar; 15(5). PMID: 36900249
The incidence of left-sided colon and rectal cancer in young people are increasing worldwide, but its causes are poorly understood. It is not clear if the tumor microenvironment is dependent...
2.
Elshami M, Goldstone R, Blaszkowsky L, Cusack Jr J, Hong T, Wo J, et al.
Dis Colon Rectum . 2022 Jun; 65(10):1224-1231. PMID: 35714358
Background: After neoadjuvant therapy, pathologic analysis of rectal cancer resected specimens may show a complete response in the primary tissue cancer with residual tumor in the lymph nodes (ypT0N+). Objectives:...
3.
Chan C, Liesenfeld L, Ferreiro-Neira I, Cusack Jr J
Ann Surg Oncol . 2016 Dec; 24(4):931-938. PMID: 27913947
Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is a treatment option for peritoneal surface malignancies. The ability to detect microscopic foci of peritoneal metastasis intraoperatively may ensure the completeness...
4.
Erstad D, Tumusiime G, Cusack Jr J
Ann Surg Oncol . 2015 Jul; 22(11):3433-50. PMID: 26215192
Colorectal cancer is a heterogeneous disease with a wide range of long-term outcomes and responses to treatment. Recent advances in the genetic and molecular characterization of tumors has yielded a...
5.
Cercek A, Cusack Jr J, Ryan D
Am Soc Clin Oncol Educ Book . 2015 May; :e208-11. PMID: 25993175
The management of peritoneal carcinomatosis from colon cancer remains a controversial issue. Peritoneal carcinomatosis is associated with worse survival and has led to an aggressive treatment that combines surgery and...
6.
Chao T, Riesel J, Anderson G, Mullen J, Doyle J, Briggs S, et al.
J Surg Educ . 2015 Feb; 72(4):e21-8. PMID: 25697510
Objective: The Massachusetts General Hospital (MGH) Department of Surgery established the Global Surgery Initiative (GSI) in 2013 to transform volunteer and mission-based global surgery efforts into an educational experience in...
7.
Erstad D, Cusack Jr J
Cancers (Basel) . 2014 Oct; 6(4):2116-36. PMID: 25329450
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine malignancy that is associated with a poor prognosis. The pathogenesis of MCC is not well understood, and despite a recent plethora...
8.
Erstad D, Cusack Jr J
Surg Oncol Clin N Am . 2013 Sep; 22(4):705-46. PMID: 24012396
Most NF-κB inhibitors target the IKK complex, IκB proteins, or NF-κB transcription factors. The most promising classes of inhibitors include antioxidants, antiinflammatory compounds, natural compounds, statins, proteasome inhibitors, IKKβ inhibitors,...
9.
Santamaria-Barria J, Boland G, Yeap B, Nardi V, Dias-Santagata D, Cusack Jr J
Ann Surg Oncol . 2012 Dec; 20(4):1365-73. PMID: 23208132
Background: Merkel cell carcinoma (MCC) is a rare cutaneous malignancy. Few single-institution series have been reported. Methods: Review of MCC patients treated at our institution between 1980 and 2010. Patient,...
10.
Drohan B, Roche C, Cusack Jr J, Hughes K
Ann Surg Oncol . 2012 Mar; 19(6):1732-7. PMID: 22427173
Purpose And Methods: Most patients who harbor a genetic mutation for hereditary breast cancer have not been identified, despite the availability of genetic testing. Developing an effective approach to the...