Francisco J Alvarez
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Explore the profile of Francisco J Alvarez including associated specialties, affiliations and a list of published articles.
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99
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2967
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Recent Articles
1.
Wood R, Calvo P, McCallum W, English A, Alvarez F
Eur J Neurosci
. 2025 Mar;
61(5):e70045.
PMID: 40068993
Motor axon regeneration after traumatic nerve injuries is a slow process that adversely influences patient outcomes because muscle reinnervation delays result in irreversible muscle atrophy and suboptimal axon regeneration. This...
2.
Worthy A, Anderson J, Lane A, Gomez-Perez L, Wang A, Griffith R, et al.
Elife
. 2024 Nov;
13.
PMID: 39607843
Spinal cord interneurons play critical roles shaping motor output, but their precise identity and connectivity remain unclear. Focusing on the V1 interneuron cardinal class we defined four major V1 subsets...
3.
Wood R, Calvo P, McCallum W, English A, Alvarez F
bioRxiv
. 2024 Nov;
PMID: 39605707
Motor axon regeneration after traumatic nerve injuries is a slow process that adversely influences patient outcomes because muscle reinnervation delays result in irreversible muscle atrophy and suboptimal axon regeneration. This...
4.
Capilla-Lopez J, Hernandez R, Carrero-Rojas G, Calvo P, Alvarez F, de la Cruz R, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337430
The potassium-chloride cotransporter KCC2 is the main extruder of Cl in neurons. It plays a fundamental role in the activity of the inhibitory neurotransmitters (GABA and glycine) since low levels...
5.
Fletcher E, Chalif J, Rotterman T, Pagiazitis J, Van Alstyne M, Sivakumar N, et al.
bioRxiv
. 2024 Sep;
PMID: 39257773
Movement is executed through the balanced action of excitatory and inhibitory neurotransmission in motor circuits of the spinal cord. Short-term perturbations in one of the two types of transmission are...
6.
Rotterman T, Haley-Johnson Z, Pottorf T, Chopra T, Chang E, Zhang S, et al.
Cell Rep
. 2024 Feb;
43(2):113776.
PMID: 38367237
Microglia-mediated synaptic plasticity after CNS injury varies depending on injury severity, but the mechanisms that adjust synaptic plasticity according to injury differences are largely unknown. This study investigates differential actions...
7.
Mistretta O, Wood R, English A, Alvarez F
J Neurophysiol
. 2024 Jan;
131(2):321-337.
PMID: 38198656
There is a lack of experimental methods in genetically tractable mouse models to analyze the developmental period at which newborns mature weight-bearing locomotion. To overcome this deficit, we introduce methods...
8.
Worthy A, Anderson J, Lane A, Gomez-Perez L, Wang A, Griffith R, et al.
bioRxiv
. 2023 Dec;
PMID: 38076820
Significance Statement: The complexity of spinal interneuron diversity and circuit organization represents a challenge to understand neural control of movement in normal adults as well as during motor development and...
9.
Alvarez F, Alvarez A, Rodriguez J, Lafuente H, Canduela M, Hind W, et al.
eNeuro
. 2023 Apr;
10(5).
PMID: 37072177
Therapeutic hypothermia is well established as a standard treatment for infants with hypoxic-ischemic (HI) encephalopathy but it is only partially effective. The potential for combination treatments to augment hypothermic neuroprotection...
10.
Calvo P, de la Cruz R, Pastor A, Alvarez F
Brain Struct Funct
. 2023 Apr;
228(3-4):967-984.
PMID: 37005931
The potassium chloride cotransporter 2 (KCC2) is the main Cl extruder in neurons. Any alteration in KCC2 levels leads to changes in Cl homeostasis and, consequently, in the polarity and...