James B Ackman
Overview
Explore the profile of James B Ackman including associated specialties, affiliations and a list of published articles.
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17
Citations
1101
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Recent Articles
1.
Weiser S, Mullen B, Ascencio D, Ackman J
PLoS Comput Biol
. 2023 May;
19(5):e1011085.
PMID: 37126531
Demixing signals in transcranial videos of neuronal calcium flux across the cerebral hemispheres is a key step before mapping features of cortical organization. Here we demonstrate that independent component analysis...
2.
Gribizis A, Ge X, Daigle T, Ackman J, Zeng H, Lee D, et al.
Neuron
. 2019 Sep;
104(4):711-723.e3.
PMID: 31561919
Visual spatial perception in the mammalian brain occurs through two parallel pathways: one reaches the primary visual cortex (V1) through the thalamus and another the superior colliculus (SC) via direct...
3.
Cuoco J, Esposito A, Moriarty S, Tang Y, Seth S, Toia A, et al.
Cerebellum
. 2017 Oct;
17(2):173-190.
PMID: 29043563
C57BL/6 mice exhibit spontaneous cerebellar malformations consisting of heterotopic neurons and glia in the molecular layer of the posterior vermis, indicative of neuronal migration defect during cerebellar development. Recognizing that...
4.
Rash B, Ackman J, Rakic P
Sci Adv
. 2016 Mar;
2(2):e1501733.
PMID: 26933693
Cortical columns are basic cellular and functional units of the cerebral cortex that are malformed in many brain disorders, but how they initially develop is not well understood. Using an...
5.
Burbridge T, Xu H, Ackman J, Ge X, Zhang Y, Ye M, et al.
Neuron
. 2014 Dec;
84(5):1049-64.
PMID: 25466916
The elaboration of nascent synaptic connections into highly ordered neural circuits is an integral feature of the developing vertebrate nervous system. In sensory systems, patterned spontaneous activity before the onset...
6.
Ackman J, Crair M
Curr Opin Neurobiol
. 2014 Feb;
24(1):166-75.
PMID: 24492092
The initial structural and functional development of visual circuits in reptiles, birds, and mammals happens independent of sensory experience. After eye opening, visual experience further refines and elaborates circuits that...
7.
Ackman J, Burbridge T, Crair M
Nature
. 2012 Oct;
490(7419):219-25.
PMID: 23060192
The morphological and functional development of the vertebrate nervous system is initially governed by genetic factors and subsequently refined by neuronal activity. However, fundamental features of the nervous system emerge...
8.
Zhang J, Ackman J, Xu H, Crair M
Nat Neurosci
. 2011 Dec;
15(2):298-307.
PMID: 22179110
Binocular competition is thought to drive eye-specific segregation in the developing visual system, potentially through Hebbian synaptic learning rules that are sensitive to correlations in afferent activity. Altering retinal activity...
9.
Zhang J, Ackman J, Dhande O, Crair M
Front Mol Neurosci
. 2011 Nov;
4:43.
PMID: 22121343
Neural activity during vertebrate development has been unambiguously shown to play a critical role in sculpting circuit formation and function. Patterned neural activity in various parts of the developing nervous...
10.
Ackman J, Aniksztejn L, Crepel V, Becq H, Pellegrino C, Cardoso C, et al.
J Neurosci
. 2009 Jan;
29(2):313-27.
PMID: 19144832
In human patients, cortical dysplasia produced by Doublecortin (DCX) mutations lead to mental retardation and intractable infantile epilepsies, but the underlying mechanisms are not known. DCX(-/-) mice have been generated...