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James A Perry

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Articles 57
Citations 1107
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Recent Articles
11.
Xu H, Nguyen K, Gaynor B, Ling H, Zhao W, McArdle P, et al.
Genes (Basel) . 2023 Jan; 14(1). PMID: 36672803
Recent genome wide association studies have identified 89 common genetic variants robustly associated with ischemic stroke and primarily located in non-coding regions. To evaluate the contribution of coding variants, which...
12.
Li J, Perry J, Jablonski K, Srinivasan S, Chen L, Todd J, et al.
Diabetes . 2022 Dec; 72(8):1161-1172. PMID: 36525397
Genome-wide significant loci for metformin response in type 2 diabetes reported elsewhere have not been replicated in the Diabetes Prevention Program (DPP). To assess pharmacogenetic interactions in prediabetes, we conducted...
13.
Baloh C, Kanchan K, Shankar G, Nepom G, Mathias R, Perry J
J Allergy Clin Immunol . 2022 Dec; 151(2):416-419. PMID: 36521801
No abstract available.
14.
Jaworek T, Xu H, Gaynor B, Cole J, Rannikmae K, Stanne T, et al.
Neurology . 2022 Oct; 99(16):e1738-e1754. PMID: 36240095
Background And Objectives: Current genome-wide association studies of ischemic stroke have focused primarily on late-onset disease. As a complement to these studies, we sought to identify the contribution of common...
15.
Alkhalfan F, Gyftopoulos A, Chen Y, Williams C, Perry J, Hong C
PLoS One . 2022 Aug; 17(8):e0273217. PMID: 35994481
Objectives: To utilize the UK Biobank to identify genetic variants associated with the ICD10 (International Classification of Diseases10)-based diagnosis of cerebrovascular disease (CeVD). Background: Cerebrovascular disease occurs because of a...
16.
DiCorpo D, Gaynor S, Russell E, Westerman K, Raffield L, Majarian T, et al.
Commun Biol . 2022 Jul; 5(1):756. PMID: 35902682
The genetic determinants of fasting glucose (FG) and fasting insulin (FI) have been studied mostly through genome arrays, resulting in over 100 associated variants. We extended this work with high-coverage...
17.
Gyftopoulos A, Chen Y, Wang L, Williams C, Chun Y, Oconnell J, et al.
Front Genet . 2022 Jun; 13:866042. PMID: 35685441
To identify previously unrecognized genetic variants and clinical variables associated with the ICD-10 (International Classification of Diseases 10)-based diagnosis of hypertrophic cardiomyopathy in the UK Biobank cohort. : Hypertrophic cardiomyopathy...
18.
Taub M, Conomos M, Keener R, Iyer K, Weinstock J, Yanek L, et al.
Cell Genom . 2022 May; 2(1). PMID: 35530816
Genetic studies on telomere length are important for understanding age-related diseases. Prior GWAS for leukocyte TL have been limited to European and Asian populations. Here, we report the first sequencing-based...
19.
Scalsky R, Chen Y, Ying Z, Perry J, Hong C
Int J Environ Res Public Health . 2022 Jan; 19(1). PMID: 35010792
COVID-19 has caused a global pandemic with considerable impact. Studies have examined the influence of socioeconomic status and air pollution on COVID-19 risk but in low detail. This study seeks...
20.
Montasser M, Van Hout C, Miloscio L, Howard A, Rosenberg A, Callaway M, et al.
Science . 2021 Dec; 374(6572):1221-1227. PMID: 34855475
Increased blood levels of low-density lipoprotein cholesterol (LDL-C) and fibrinogen are independent risk factors for cardiovascular disease. We identified associations between an Amish-enriched missense variant (p.Asn352Ser) in a functional domain...