James A McLaughlin
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Explore the profile of James A McLaughlin including associated specialties, affiliations and a list of published articles.
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20
Citations
100
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Recent Articles
1.
Matentzoglu N, Bello S, Stefancsik R, Alghamdi S, Anagnostopoulos A, Balhoff J, et al.
Genetics
. 2025 Mar;
PMID: 40048704
Phenotypic data are critical for understanding biological mechanisms and consequences of genomic variation, and are pivotal for clinical use cases such as disease diagnostics and treatment development. For over a...
2.
Caron A, Puig-Barbe A, Quardokus E, Balhoff J, Belfiore J, Chipampe N, et al.
bioRxiv
. 2025 Jan;
PMID: 39763856
Annotation with widely used, well-structured ontologies, combined with the use of ontology-aware software tools, ensures data and analyses are Findable, Accessible, Interoperable and Reusable (FAIR). Standardized terms with synonyms support...
3.
Matentzoglu N, Bello S, Stefancsik R, Alghamdi S, Anagnostopoulos A, Balhoff J, et al.
bioRxiv
. 2024 Sep;
PMID: 39345458
Phenotypic data are critical for understanding biological mechanisms and consequences of genomic variation, and are pivotal for clinical use cases such as disease diagnostics and treatment development. For over a...
4.
Bridges Y, de Souza V, Cortes K, Haendel M, Harris N, Korn D, et al.
bioRxiv
. 2024 Jun;
PMID: 38915571
Background: Computational approaches to support rare disease diagnosis are challenging to build, requiring the integration of complex data types such as ontologies, gene-to-phenotype associations, and cross-species data into variant and...
5.
Huang J, Wang H, Power U, McLaughlin J, Nugent C, Rahman E, et al.
Sensors (Basel)
. 2024 Jan;
24(1).
PMID: 38203170
Respiratory viruses' detection is vitally important in coping with pandemics such as COVID-19. Conventional methods typically require laboratory-based, high-cost equipment. An emerging alternative method is Near-Infrared (NIR) spectroscopy, especially a...
6.
Putman T, Schaper K, Matentzoglu N, Rubinetti V, Alquaddoomi F, Cox C, et al.
Nucleic Acids Res
. 2023 Nov;
52(D1):D938-D949.
PMID: 38000386
Bridging the gap between genetic variations, environmental determinants, and phenotypic outcomes is critical for supporting clinical diagnosis and understanding mechanisms of diseases. It requires integrating open data at a global...
7.
Bradley Z, Coleman P, Courtney M, Fishlock S, McGrath J, Uniacke-Lowe T, et al.
ACS Omega
. 2023 Mar;
8(9):8407-8414.
PMID: 36910974
Sepsis is the body's response to an infection. Existing diagnostic testing equipment is not available in primary care settings and requires long waiting times. Lateral flow devices (LFDs) could be...
8.
Bhattacharya G, Fishlock S, Hussain S, Choudhury S, Xiang A, Kandola B, et al.
ACS Appl Mater Interfaces
. 2022 Jun;
14(27):31109-31120.
PMID: 35767835
Laser-induced graphene (LIG) on paper substrates is a desirable material for single-use point-of-care sensing with its high-quality electrical properties, low fabrication cost, and ease of disposal. While a prior study...
9.
Matentzoglu N, Balhoff J, Bello S, Bizon C, Brush M, Callahan T, et al.
Database (Oxford)
. 2022 May;
2022.
PMID: 35616100
Despite progress in the development of standards for describing and exchanging scientific information, the lack of easy-to-use standards for mapping between different representations of the same or similar objects in...
10.
Hatch B, Meng L, Mante J, McLaughlin J, Scott-Brown J, Myers C
ACS Synth Biol
. 2021 Jul;
10(8):2111-2115.
PMID: 34324811
VisBOL is a web-based visualization tool used to depict genetic circuit designs. This tool depicts simple DNA circuits adequately, but it has become increasingly outdated as new versions of SBOL...