James A McKinnell
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Explore the profile of James A McKinnell including associated specialties, affiliations and a list of published articles.
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71
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1372
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Recent Articles
1.
Gussin G, McKinnell J, Singh R, Miller L, Kleinman K, Saavedra R, et al.
JAMA
. 2024 Apr;
331(18):1544-1557.
PMID: 38557703
Importance: Infections due to multidrug-resistant organisms (MDROs) are associated with increased morbidity, mortality, length of hospitalization, and health care costs. Regional interventions may be advantageous in mitigating MDROs and associated...
2.
Ojala F, Sater M, Miller L, McKinnell J, Hayden M, Huang S, et al.
PLoS Comput Biol
. 2023 Oct;
19(10):e1010898.
PMID: 37883601
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of morbidity and mortality. Colonization by MRSA increases the risk of infection and transmission, underscoring the importance of decolonization efforts. However, success...
3.
Miller L, McKinnell J, Singh R, Gussin G, Kleinman K, Saavedra R, et al.
N Engl J Med
. 2023 Oct;
389(19):1766-1777.
PMID: 37815935
Background: Nursing home residents are at high risk for infection, hospitalization, and colonization with multidrug-resistant organisms. Methods: We performed a cluster-randomized trial of universal decolonization as compared with routine-care bathing...
4.
Waters M, McKinnell J, Kalil A, Martin G, Buchman T, Theess W, et al.
Crit Care Med
. 2022 Dec;
51(1):103-116.
PMID: 36519984
Objectives: Severe cases of COVID-19 pneumonia can lead to acute respiratory distress syndrome (ARDS). Release of interleukin (IL)-33, an epithelial-derived alarmin, and IL-33/ST2 pathway activation are linked with ARDS development...
5.
Amin A, Dellinger E, Harnett G, Kraft B, LaPlante K, LoVecchio F, et al.
Front Med (Lausanne)
. 2022 Aug;
9:901980.
PMID: 35966853
Antibiotic-resistant pathogens cause over 35,000 preventable deaths in the United States every year, and multiple strategies could decrease morbidity and mortality. As antibiotic stewardship requirements are being deployed for the...
6.
Poyraz O, Sater M, Miller L, McKinnell J, Huang S, Grad Y, et al.
J R Soc Interface
. 2022 Jun;
19(191):20210916.
PMID: 35702866
Methicillin-resistant (MRSA) can colonize multiple body sites, and carriage is a risk factor for infection. Successful decolonization protocols reduce disease incidence; however, multiple protocols exist, comprising diverse therapies targeting multiple...
7.
Miller L, Singh R, Eells S, Gillen D, McKinnell J, Park S, et al.
Clin Infect Dis
. 2022 May;
76(3):e1208-e1216.
PMID: 35640877
Background: The CLEAR Trial demonstrated that a multisite body decolonization regimen reduced post-discharge infection and hospitalization in methicillin-resistant Staphylococcus aureus (MRSA) carriers. Here, we describe decolonization efficacy. Methods: We performed...
8.
Gussin G, Heim L, Tjoa T, McKinnell J, Miller L, Gillen D, et al.
Infect Control Hosp Epidemiol
. 2021 Dec;
44(2):315-318.
PMID: 34913422
The CLEAR Trial recently found that decolonization reduced infections and hospitalizations in MRSA carriers in the year following hospital discharge. In this secondary analysis, we explored whether decolonization had a...
9.
Heim L, Miller L, Singh R, McKinnell J, Catuna T, Estevez M, et al.
Infect Control Hosp Epidemiol
. 2021 Aug;
43(12):1937-1939.
PMID: 34433509
In a prospective cohort study, we compared a 2-swabs-per-nostril 5% iodophor regimen with a 1-swab-per-nostril 10% iodophor regimen on methicillin-resistant carriage in nursing-home residents. Compared with baseline, both single-swab and...
10.
Bartsch S, Wong K, Mueller L, Gussin G, McKinnell J, Tjoa T, et al.
JAMA Netw Open
. 2021 Aug;
4(8):e2119212.
PMID: 34347060
Importance: Multidrug-resistant organisms (MDROs) can spread across health care facilities in a region. Because of limited resources, certain interventions can be implemented in only some facilities; thus, decision-makers need to...