James A L Brown
Overview
Explore the profile of James A L Brown including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
769
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0
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Recent Articles
1.
Zohourian N, Coll E, Dever M, Sheahan A, Burns-Lane P, Brown J
Cancers (Basel)
. 2024 Aug;
16(15).
PMID: 39123405
Precision (individualized) medicine relies on the molecular profiling of tumors' dysregulated characteristics (genomic, epigenetic, transcriptomic) to identify the reliance on key pathways (including genome stability and epigenetic gene regulation) for...
2.
Prakash A, Paunikar S, Webber M, McDermott E, Vellanki S, Thompson K, et al.
J Cell Sci
. 2023 Sep;
136(21).
PMID: 37772773
Centrosome amplification (CA) is a prominent feature of human cancers linked to tumorigenesis in vivo. Here, we report mechanistic contributions of CA induction alone to tumour architecture and extracellular matrix...
3.
Brown J
PLoS One
. 2023 Jun;
18(6):e0286826.
PMID: 37285357
The development and practice of good leadership skills (distinct from management skills) enhances both an individual's career development, and their organization. However, universities are known to present unique issues around...
4.
Jalali A, Miresse D, Fahey M, Ni Mhaonaigh N, McGuire A, Bourke E, et al.
Curr Oncol
. 2022 Oct;
29(10):7512-7523.
PMID: 36290868
Breast cancer represents a heterogeneous condition in which the interaction between host immune response and primary oncogenic events can impact disease progression. Ratios of systemic blood-based immunocytes have emerged as...
5.
Brown J, Bourke E, Hancock W, Richard D
Front Cell Dev Biol
. 2022 Sep;
10:974545.
PMID: 36046336
No abstract available.
6.
Suraweera A, Brown J, Lim Y, Lavin M
Front Mol Biosci
. 2022 Mar;
9:858514.
PMID: 35242815
No abstract available.
7.
Chen L, Kong X, Fang Y, Paunikar S, Wang X, Brown J, et al.
Front Cell Dev Biol
. 2021 Nov;
9:747314.
PMID: 34805157
Discoidin domain receptor tyrosine kinases (DDRs) are a class of receptor tyrosine kinases (RTKs), and their dysregulation is associated with multiple diseases (including cancer, chronic inflammatory conditions, and fibrosis). The...
8.
Likhatcheva M, Gieling R, Brown J, Demonacos C, Williams K
Front Cell Dev Biol
. 2021 Oct;
9:720194.
PMID: 34621741
The effects of genotoxic stress can be mediated by activation of the Ataxia Telangiectasia Mutated (ATM) kinase, under both DNA damage-dependent (including ionizing radiation), and independent (including hypoxic stress) conditions....
9.
McGuire A, Casey M, Waldron R, Heneghan H, Kalinina O, Holian E, et al.
Cancers (Basel)
. 2020 Jul;
12(7).
PMID: 32645898
Neoadjuvant chemotherapy (NACT) is used in locally advanced breast cancer to reduce tumour burden prior to surgical resection. However, only a subset of NACT treated patients will respond to treatment...
10.
Kong X, Zhai J, Yan C, Song Y, Wang J, Bai X, et al.
Front Oncol
. 2019 Jun;
9:234.
PMID: 31214487
FOXN3 (forkhead box N3; CHES1: check point suppressor 1) belongs to the forkhead box (FOX) protein family. FOXN3 displays transcriptional inhibitory activity, and is involved in cell cycle regulation and...