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Jakob Starzyk

Explore the profile of Jakob Starzyk including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Xie K, Starzyk J, Majumdar I, Wang J, Rincones K, Tran T, et al.
Nat Biotechnol . 2024 Dec; PMID: 39663372
The use of adeno-associated viruses (AAVs) as donors for homology-directed repair (HDR)-mediated genome engineering is limited by safety issues, manufacturing constraints and restricted packaging limits. Non-viral targeted genetic knock-ins rely...
2.
Nam H, Xie K, Majumdar I, Yang S, Starzyk J, Lee D, et al.
Res Sq . 2023 Nov; PMID: 37961210
Non-viral DNA donor template has been widely used for targeted genomic integration by homologous recombination (HR). This process has become more efficient with RNA guided endonuclease editor system such as...
3.
Nam H, Xie K, Majumdar I, Yang S, Starzyk J, Lee D, et al.
bioRxiv . 2023 Sep; PMID: 37693500
Highlight: A reporter Knock-in screening establishes enGager system to identify TESOGENASE editor to improving ssDNA mediated genome integrationMini-TESOGENASEs developed by fusing Cas9 nuclease with novel ssDNA binding motifsmRNA mini-TESOGENASEs enhance...