Jakob M Bader
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Explore the profile of Jakob M Bader including associated specialties, affiliations and a list of published articles.
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8
Citations
493
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Recent Articles
1.
Bader J, Albrecht V, Mann M
Mol Cell Proteomics
. 2023 May;
22(7):100577.
PMID: 37209816
Accurate biomarkers are a crucial and necessary precondition for precision medicine, yet existing ones are often unspecific and new ones have been very slow to enter the clinic. Mass spectrometry...
2.
Thomas F, Omnus D, Bader J, Chung G, Kono N, Stefan C
Life Sci Alliance
. 2022 Apr;
5(8).
PMID: 35440494
The evolutionarily conserved extended synaptotagmin (E-Syt) proteins are calcium-activated lipid transfer proteins that function at contacts between the ER and plasma membrane (ER-PM contacts). However, roles of the E-Syt family...
3.
Fitzner D, Bader J, Penkert H, Bergner C, Su M, Weil M, et al.
Cell Rep
. 2020 Sep;
32(11):108132.
PMID: 32937123
Gene and protein expression data provide useful resources for understanding brain function, but little is known about the lipid composition of the brain. Here, we perform quantitative shotgun lipidomics, which...
4.
Muller J, Geyer P, Colaco A, Treit P, Strauss M, Oroshi M, et al.
Nature
. 2020 Jun;
582(7813):592-596.
PMID: 32555458
Proteins carry out the vast majority of functions in all biological domains, but for technological reasons their large-scale investigation has lagged behind the study of genomes. Since the first essentially...
5.
Bader J, Geyer P, Muller J, Strauss M, Koch M, Leypoldt F, et al.
Mol Syst Biol
. 2020 Jun;
16(6):e9356.
PMID: 32485097
Neurodegenerative diseases are a growing burden, and there is an urgent need for better biomarkers for diagnosis, prognosis, and treatment efficacy. Structural and functional brain alterations are reflected in the...
6.
Omnus D, Cadou A, Thomas F, Bader J, Soh N, Chung G, et al.
BMC Biol
. 2020 Mar;
18(1):28.
PMID: 32169085
Background: Phosphoinositide lipids provide spatial landmarks during polarized cell growth and migration. Yet how phosphoinositide gradients are oriented in response to extracellular cues and environmental conditions is not well understood....
7.
Geyer P, Voytik E, Treit P, Doll S, Kleinhempel A, Niu L, et al.
EMBO Mol Med
. 2019 Oct;
11(11):e10427.
PMID: 31566909
Plasma and serum are rich sources of information regarding an individual's health state, and protein tests inform medical decision making. Despite major investments, few new biomarkers have reached the clinic....
8.
Omnus D, Manford A, Bader J, Emr S, Stefan C
Mol Biol Cell
. 2016 Feb;
27(7):1170-80.
PMID: 26864629
Membrane lipid dynamics must be precisely regulated for normal cellular function, and disruptions in lipid homeostasis are linked to the progression of several diseases. However, little is known about the...