Jakob M A Mauritz
Overview
Explore the profile of Jakob M A Mauritz including associated specialties, affiliations and a list of published articles.
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8
Citations
186
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Recent Articles
1.
Mauritz J, Seear R, Esposito A, Kaminski C, Skepper J, Warley A, et al.
Biophys J
. 2011 Mar;
100(6):1438-45.
PMID: 21402025
Plasmodium falciparum is responsible for severe malaria. During the ∼48 h duration of its asexual reproduction cycle in human red blood cells, the parasite causes profound alterations in the homeostasis...
2.
Swietach P, Tiffert T, Mauritz J, Seear R, Esposito A, Kaminski C, et al.
J Physiol
. 2010 Oct;
588(Pt 24):4995-5014.
PMID: 20962000
Our understanding of pH regulation within red blood cells (RBCs) has been inferred mainly from indirect experiments rather than from in situ measurements of intracellular pH (pH(i)). The present work...
3.
Esposito A, Choimet J, Skepper J, Mauritz J, Lew V, Kaminski C, et al.
Biophys J
. 2010 Aug;
99(3):953-60.
PMID: 20682274
During its 48 h asexual reproduction cycle, the malaria parasite Plasmodium falciparum ingests and digests hemoglobin in excess of its metabolic requirements and causes major changes in the homeostasis of...
4.
Mauritz J, Esposito A, Tiffert T, Skepper J, Warley A, Yoon Y, et al.
Med Biol Eng Comput
. 2010 Jul;
48(10):1055-63.
PMID: 20661776
Investigation of the homeostasis of red blood cells upon infection by Plasmodium falciparum poses complex experimental challenges. Changes in red cell shape, volume, protein, and ion balance are difficult to...
5.
Mauritz J, Tiffert T, Seear R, Lautenschlager F, Esposito A, Lew V, et al.
J Biomed Opt
. 2010 Jul;
15(3):030517.
PMID: 20615000
We present the application of a microfluidic optical cell stretcher to measure the elasticity of malaria-infected red blood cells. The measurements confirm an increase in host cell rigidity during the...
6.
Mauritz J, Morrisby R, Hutton R, Legge C, Kaminski C
J Pharm Sci
. 2009 Jun;
99(1):385-91.
PMID: 19544370
Optical coherence tomography (OCT) is a recently developed optical technique that produces depth profiles of three-dimensional objects. It is a nondestructive interferometric method responding to refractive index variation in the...
7.
Mauritz J, Esposito A, Ginsburg H, Kaminski C, Tiffert T, Lew V
PLoS Comput Biol
. 2009 Apr;
5(4):e1000339.
PMID: 19343220
The asexual reproduction cycle of Plasmodium falciparum, the parasite responsible for severe malaria, occurs within red blood cells. A merozoite invades a red cell in the circulation, develops and multiplies,...
8.
Esposito A, Tiffert T, Mauritz J, Schlachter S, Bannister L, Kaminski C, et al.
PLoS One
. 2008 Nov;
3(11):e3780.
PMID: 19023444
Background: During its intraerythrocytic asexual reproduction cycle Plasmodium falciparum consumes up to 80% of the host cell hemoglobin, in large excess over its metabolic needs. A model of the homeostasis...