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Jaisan Islam

Explore the profile of Jaisan Islam including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 61
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Recent Articles
1.
Islam J, Rahman M, Ali M, Kim H, Kc E, Park Y
J Headache Pain . 2025 Feb; 26(1):41. PMID: 39994518
Background: Trigeminal neuropathic pain (TNP) is a chronic condition characterized by heightened nociceptive responses and neuroinflammatory changes. While astrocytes are recognized as critical players in pain modulation, their specific role...
2.
Islam J, Rahman M, Ali M, Kc E, Park Y
J Headache Pain . 2024 Nov; 25(1):205. PMID: 39587517
Trigeminal neuropathic pain (TNP), migraine, and cluster headache (CH) profoundly impact the quality of life and present significant clinical challenges due to their complex neurobiological underpinnings. This review delves into...
3.
Islam J, Rahman M, Kc E, Park Y
J Headache Pain . 2024 May; 25(1):76. PMID: 38730344
Trigeminal neuropathic pain (TNP) is a major concern in both dentistry and medicine. The progression from normal to chronic TNP through activation of the insular cortex (IC) is thought to...
4.
Kc E, Islam J, Kim H, Park Y
J Headache Pain . 2023 Oct; 24(1):137. PMID: 37821818
The significance of hyperactive astrocytes in neuropathic pain is crucial. However, the association between medullary astrocytes and trigeminal neuralgia (TN)-related pain processing is unclear. Here, we examined how optogenetic inhibition...
5.
Kc E, Islam J, Lee G, Park Y
Mol Neurobiol . 2023 Sep; 61(3):1769-1780. PMID: 37775720
The integration of optogenetics in the trigeminal pain circuitry broadens and reinforces existing pain investigations. Similar to research on spinal neuropathic pain, the exploration of the underlying determinants of orofacial...
6.
Islam J, Kc E, Kim S, Chung M, Park K, Kim H, et al.
Neuromolecular Med . 2023 Sep; 25(4):516-532. PMID: 37700212
In individuals with chronic neuropathic pain, the posterior insular cortex (PIC) has been found to exhibit increased glutamatergic activity, and the dysgranular portion of PIC (DPIC) has been investigated as...
7.
Islam J, Kc E, So K, Kim S, Kim H, Park Y, et al.
Sci Rep . 2023 Jan; 13(1):489. PMID: 36627362
Posterior hypothalamus (PH), an important part of the descending pain processing pathway, has been found to be activated in trigeminal autonomic cephalalgias. However, there are very few studies conducted and...
8.
Kc E, Islam J, Park Y
J Headache Pain . 2022 Nov; 23(1):150. PMID: 36424545
Excruciating trigeminal neuralgia (TN) management is very difficult and severely affects the patient's quality of life. Earlier studies have shown that the trigeminal ganglion (TG) comprises several receptors and signal...
9.
Kc E, Islam J, Kim S, Kim H, Park Y
Front Cell Neurosci . 2022 May; 16:880369. PMID: 35573830
The trigeminal ganglion (TG) is the primary site of aberration in trigeminal neuralgia (TN), and hence a crucial site where afferent input can be modulated. Here, we postulated that inhibiting...
10.
Islam J, So K, Kc E, Moon H, Kim A, Hyun S, et al.
Stem Cell Res Ther . 2021 Nov; 12(1):585. PMID: 34809707
Background: Human embryonic stem cells (hESCs) transplantation had shown to provide a potential source of cells in neurodegenerative disease studies and lead to behavioral recovery in lentivirus transfected or, toxin-induced...