Jai-Shin Liu
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Explore the profile of Jai-Shin Liu including associated specialties, affiliations and a list of published articles.
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22
Citations
211
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Recent Articles
1.
Huang C, Tsai Y, Cheng Y, Wu P, Chuang Y, Huang P, et al.
Gene Ther
. 2024 Sep;
31(11-12):531-540.
PMID: 39232211
SLC26A4 encodes pendrin, a crucial anion exchanger essential for maintaining hearing function. Mutations in SLC26A4, including the prevalent c.919-2 A > G splice-site mutation among East Asian individuals, can disrupt...
2.
Li H, Huang C, Lui K, Chao Y, Yeh C, Lee L, et al.
Transl Oncol
. 2023 Sep;
38:101785.
PMID: 37713975
Background: Nasopharyngeal carcinoma (NPC) is associated with Epstein-Barr virus (EBV) infection. To test preclinical NPC drugs, we established two patient-derived xenograft (PDX) mouse models, EBV-positive PDX-B13 and EBV-negative PDX-Li41, for...
3.
Liu J, Fang W, Yang S, Wu M, Chen T, Chen C, et al.
J Biomed Sci
. 2022 May;
29(1):29.
PMID: 35534851
Background: Castration-resistant prostate cancer (CRPC) with sustained androgen receptor (AR) signaling remains a critical clinical challenge, despite androgen depletion therapy. The Jumonji C-containing histone lysine demethylase family 4 (KDM4) members,...
4.
Kuo Y, Huo C, Lin C, Lin H, Liu J, Wang W, et al.
Cell Commun Signal
. 2019 Aug;
17(1):100.
PMID: 31429764
Background: Androgen receptor (AR) plays important role in the development, progression, and metastasis of prostate cancer (PCa). Caffeic acid phenethyl ester (CAPE) is the main component of honey bee propolis....
5.
Chen T, Wang H, Liu J, Cheng H, Hsu S, Wu M, et al.
Commun Biol
. 2019 Mar;
2:105.
PMID: 30911680
PKM2 is a key metabolic enzyme central to glucose metabolism and energy expenditure. Multiple stimuli regulate PKM2's activity through allosteric modulation and post-translational modifications. Furthermore, PKM2 can partner with KDM8,...
6.
Lai C, Huang J, Cheng H, Wu M, Huang M, Hsu H, et al.
Cell Microbiol
. 2018 Aug;
20(12):e12947.
PMID: 30151951
Cholesterol-α-glucosyltransferase (CGT) encoded by the type 1 capsular polysaccharide biosynthesis protein J (capJ) gene of Helicobacter pylori converts cellular cholesterol into cholesteryl glucosides. H. pylori infection induces autophagy that may...
7.
Liu J, Kuan Y, Tsou Y, Lin T, Hsu W, Yang M, et al.
Sci Rep
. 2018 Feb;
8(1):2316.
PMID: 29396495
Bioconversion is useful to produce optically pure enantiomers in the pharmaceutical industry, thereby avoiding problems with side reactions during organic synthesis processes. A short-chain dehydrogenase/reductase from Serratia marcescens BCRC 10948...
8.
Hsu C, Liu J, Lin T, Chang Y, Kuo Y, Lin A, et al.
Oncotarget
. 2017 Oct;
8(41):69508-69519.
PMID: 29050220
Using bicalutamide-androgen receptor (AR) DNA binding domain-ligand binding domain as bait, we observed enrichment of FxxFY motif-containing peptides. Protein database searches revealed the presence of receptor-interacting protein kinase 1 (RIPK1)...
9.
Chen S, Huang C, Lai S, Liu J, Fu P, Tseng S, et al.
Sci Rep
. 2015 May;
5:10100.
PMID: 25960001
Streptosporangium sibiricum SibL catalyzes the methyl transfer from S-adenosylmethionine (SAM) to 3-hydroxykynurenine (3-HK) to produce S-adenosylhomocysteine (SAH) and 3-hydroxy-4-methyl-kynurenine for sibiromycin biosynthesis. Here, we present the crystal structures of apo-form...
10.
Hsu C, Liu J, Wu P, Guan H, Chen Y, Lin A, et al.
Mol Oncol
. 2014 Aug;
8(8):1575-87.
PMID: 25091737
Treatment with individual anti-androgens is associated with the development of hot-spot mutations in the androgen receptor (AR). Here, we found that anti-androgens-mt-ARs have similar binary structure to the 5α-dihydrotestosterone-wt-AR. Phage...