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Jae Geun Song

Explore the profile of Jae Geun Song including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 234
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Recent Articles
1.
Kim G, Song J, Han H
Pharmaceutics . 2024 Jul; 16(7). PMID: 39065583
This study aimed to develop an effective oral formulation of semaglutide, a glucagon-like peptide-1 receptor agonist, using an organometallic phyllosilicate-based colonic delivery system. The core nanocomplex (AMP-Sema) of 3-aminopropyl-functionalized magnesium...
2.
Baral K, Lee S, Song J, Jeong S, Han H
Pharmaceutics . 2023 Dec; 15(12). PMID: 38140061
MT-102 is a new anti-inflammatory agent derived from and . Its therapeutic potential is hindered by low aqueous solubility, impacting its in vivo efficacy. Therefore, this study aimed to develop...
3.
Bajracharya R, Baral K, Lee S, Song J, Han H
Int J Nanomedicine . 2023 Dec; 18:7257-7266. PMID: 38076733
Purpose: Oral administration, although convenient and preferred for treating colorectal cancer (CRC), faces challenges due to limited CRC-related intestinal positioning and a dense mucus barrier. In the present study, a...
4.
Park H, Harmalkar D, Wei J, Sun S, Kwon J, Lee C, et al.
Eur J Med Chem . 2023 Oct; 261:115864. PMID: 37839347
Leukotriene B4 (LTB4) is a potent chemoattractant that can recruit and activate immune cells such as neutrophils, eosinophils, and monocytes to sites of inflammation. Excessive production of LTB4 has been...
5.
Song J, Kim D, Han H
Int J Nanomedicine . 2023 Jul; 18:3937-3949. PMID: 37489139
Purpose: Oral administration of liraglutide, a protein drug, suffers from low intestinal absorption and instability in the gastrointestinal tract, resulting in low bioavailability. The present study aimed to develop a...
6.
Song J, Baral K, Kim G, Park J, Seo S, Kim D, et al.
Drug Deliv . 2023 Mar; 30(1):2183816. PMID: 36880122
Pharmaceutical application of therapeutic proteins has been continuously expanded for the treatment of various diseases. Efficient and reliable bioanalytical methods are essential to expedite the identification and successful clinical development...
7.
Park H, Lee S, Song J, Van Kaer L, Cheon J, Lim S, et al.
Molecules . 2022 Dec; 27(24). PMID: 36557876
Although 3-aminopropyl functionalized magnesium phyllosilicate nanoparticles (hereafter aminoclay nanoparticles, ACNs) are well-known nanomaterials employed as drug carriers, their effects on immune cells remain unclear. To address this issue, we explored...
8.
Lee S, Song J, Han H
Acta Pharm Sin B . 2022 Nov; 12(11):4249-4261. PMID: 36386471
This study aimed to develop a pH-responsive folic acid-grafted organic/inorganic hybrid nanocomposite system for site-selective oral delivery of therapeutic antibodies. A folic acid-grafted aminoclay (FA-AC) was prepared an sol‒gel method....
9.
Song J, Noh H, Lee S, Han H
Pharmaceutics . 2022 Nov; 14(11). PMID: 36365088
This study was conducted to develop a lipid/clay-based solid dispersion (LSD) formulation to enhance the dissolution and oral bioavailability of poorly soluble curcumin. Krill oil and aminoclay were used as...
10.
Bajracharya R, Song J, Lee S, Jeong S, Han H
Pharmaceutics . 2022 Jul; 14(7). PMID: 35890405
This study aimed to develop a solid dispersion (SD) of MT-102, a new anti-inflammatory agent, to improve its oral bioavailability. The ternary SD formulations of MT-102 (a poorly soluble extract...