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Jae Bum Kim

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Articles 157
Citations 5645
Followers 0
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Recent Articles
1.
Lee C, Park C, Kim H, Jang W, Min S, Kim J, et al.
Diabetes Metab J . 2025 Mar; PMID: 40068621
Background: Chronic low-grade inflammation in multiple metabolic organs contributes to the development of insulin resistance induced by obesity. Progranulin (PGRN) is an evolutionarily-conserved secretory protein implicated in immune modulation. The...
2.
Ji Y, Jeon Y, Lee W, Han J, Shin K, Huh J, et al.
Mol Cells . 2024 Nov; 47(12):100149. PMID: 39547583
Autophagy is a crucial intracellular degradation process that provides energy and supports nutrient deprivation adaptation. However, the mechanisms by which these cells detect lipid scarcity and regulate autophagy are poorly...
3.
Jeon Y, Kim S, Kim J
Adipocyte . 2024 Aug; 13(1):2391511. PMID: 39155481
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue (WAT) play pivotal roles in maintaining body temperature and energy metabolism. In mice, BAT quickly stimulates thermogenesis...
4.
Han S, Nahmgoong H, Yim K, Kim J
Trends Endocrinol Metab . 2024 Aug; 36(2):147-160. PMID: 39095230
Cellular turnover is fundamental for tissue homeostasis and integrity. Adipocyte turnover, accounting for 4% of the total cellular mass turnover in humans, is essential for adipose tissue homeostasis during metabolic...
5.
Song Y, Na H, Lee S, Kim Y, Moon J, Nam T, et al.
Nat Commun . 2024 Jul; 15(1):5623. PMID: 38965229
No abstract available.
6.
Choi S, Kang J, Tran Y, Jeong S, Park K, Shin H, et al.
Nat Metab . 2024 May; 6(5):847-860. PMID: 38811804
Adipose tissues serve as an energy reservoir and endocrine organ, yet the mechanisms that coordinate these functions remain elusive. Here, we show that the transcriptional coregulators, YAP and TAZ, uncouple...
7.
Song Y, Na H, Lee S, Kim Y, Moon J, Nam T, et al.
Nat Commun . 2024 May; 15(1):4052. PMID: 38744820
Obesity has emerged as a prominent risk factor for the development of malignant tumors. However, the existing literature on the role of adipocytes in the tumor microenvironment (TME) to elucidate...
8.
Jo J, Jang W, Park N, Kim Y, Kim J, Song K
J Chest Surg . 2024 Apr; 57(4):399-407. PMID: 38584376
Background: Pump-controlled retrograde trial off (PCRTO) is a safe, simple, and reversible method for weaning patients from veno-arterial extracorporeal membrane oxygenation (VA-ECMO). However, few studies have compared PCRTO to conventional...
9.
Jeon Y, Nahmgoong H, Oh J, Lee D, Kim D, Kim J, et al.
Nat Commun . 2024 Jan; 15(1):940. PMID: 38296968
In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli. BAT rapidly generates heat through brown adipocyte activation,...
10.
Chan Yu H, Jeon Y, Na A, Han C, Lee M, Yang J, et al.
Nat Metab . 2024 Jan; 6(1):94-112. PMID: 38216738
Adipose tissue lipolysis is mediated by cAMP-protein kinase A (PKA)-dependent intracellular signalling. Here, we show that PKA targets p21-activated kinase 4 (PAK4), leading to its protein degradation. Adipose tissue-specific overexpression...